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Page 1
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.
Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M. Frodermann V, et al. Among authors: lee ih. Nat Med. 2019 Nov;25(11):1761-1771. doi: 10.1038/s41591-019-0633-x. Epub 2019 Nov 7. Nat Med. 2019. PMID: 31700184 Free PMC article.
Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases.
Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, Naxerova K. Reiter JG, et al. Among authors: lee ih. Nat Genet. 2020 Jul;52(7):692-700. doi: 10.1038/s41588-020-0633-2. Epub 2020 May 25. Nat Genet. 2020. PMID: 32451459 Free PMC article.
PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.
Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. Zhang Y, et al. Among authors: lee ih. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2023373118. doi: 10.1073/pnas.2023373118. Proc Natl Acad Sci U S A. 2021. PMID: 34330826 Free PMC article.
B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.
Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, Yamazoe M, Schmidt SP, Wojtkiewicz GR, Masson GS, Gustafsson K, Capen D, Brown D, Higgins JM, Scadden DT, Libby P, Swirski FK, Naxerova K, Nahrendorf M. Schloss MJ, et al. Among authors: lee ih. Nat Immunol. 2022 Apr;23(4):605-618. doi: 10.1038/s41590-022-01165-7. Epub 2022 Mar 28. Nat Immunol. 2022. PMID: 35352063 Free PMC article.
Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.
Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, Yamazoe M, Schmidt SP, Wojtkiewicz GR, Masson GS, Gustafsson K, Capen D, Brown D, Higgins JM, Scadden DT, Libby P, Swirski FK, Naxerova K, Nahrendorf M. Schloss MJ, et al. Among authors: lee ih. Nat Immunol. 2022 Aug;23(8):1285. doi: 10.1038/s41590-022-01266-3. Nat Immunol. 2022. PMID: 35705799 No abstract available.
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease.
Rohde D, Vandoorne K, Lee IH, Grune J, Zhang S, McAlpine CS, Schloss MJ, Nayar R, Courties G, Frodermann V, Wojtkiewicz G, Honold L, Chen Q, Schmidt S, Iwamoto Y, Sun Y, Cremer S, Hoyer FF, Iborra-Egea O, Muñoz-Guijosa C, Ji F, Zhou B, Adams RH, Wythe JD, Hidalgo J, Watanabe H, Jung Y, van der Laan AM, Piek JJ, Kfoury Y, Désogère PA, Vinegoni C, Dutta P, Sadreyev RI, Caravan P, Bayes-Genis A, Libby P, Scadden DT, Lin CP, Naxerova K, Swirski FK, Nahrendorf M. Rohde D, et al. Among authors: lee ih. Nat Cardiovasc Res. 2022 Jan;1(1):28-44. doi: 10.1038/s44161-021-00002-8. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35747128 Free PMC article.
Recruited macrophages elicit atrial fibrillation.
Hulsmans M, Schloss MJ, Lee IH, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous FE, Keller D, Bening C, Green U, Lennerz JK, Mitchell RN, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong CS, Pierson RN, Aster JC, Rohde D, Wojtkiewicz GR, Weissleder R, Swirski FK, Tellides G, Tolis G Jr, Melnitchouk S, Milan DJ, Ellinor PT, Naxerova K, Nahrendorf M. Hulsmans M, et al. Among authors: lee ih. Science. 2023 Jul 14;381(6654):231-239. doi: 10.1126/science.abq3061. Epub 2023 Jul 13. Science. 2023. PMID: 37440641 Free PMC article.
Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction.
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee IH, Mentkowski K, Grune J, Schloss MJ, Honold L, Iwamoto Y, Zheng Y, Bredella MA, Buckless C, Ghoshhajra B, Thondapu V, van der Laan AM, Piek JJ, Niessen HWM, Pallante F, Carnevale R, Perrotta S, Carnevale D, Iborra-Egea O, Muñoz-Guijosa C, Galvez-Monton C, Bayes-Genis A, Vidoudez C, Trauger SA, Scadden D, Swirski FK, Moskowitz MA, Naxerova K, Nahrendorf M. Zhang S, et al. Among authors: lee ih. Nat Cardiovasc Res. 2023 Dec;2(12):1277-1290. doi: 10.1038/s44161-023-00388-7. Epub 2023 Dec 5. Nat Cardiovasc Res. 2023. PMID: 38344689 Free PMC article.
Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation.
Momin N, Pabel S, Rudra A, Kumowski N, Lee IH, Mentkowski K, Yamazoe M, Stengel L, Muse CG, Seung H, Paccalet A, Gonzalez-Correa C, Jacobs EB, Grune J, Schloss MJ, Sossalla S, Wojtkiewicz G, Iwamoto Y, McMullen P, Mitchell RN, Ellinor PT, Anderson DG, Naxerova K, Nahrendorf M, Hulsmans M. Momin N, et al. Among authors: lee ih. bioRxiv [Preprint]. 2024 Aug 10:2024.08.10.607461. doi: 10.1101/2024.08.10.607461. bioRxiv. 2024. PMID: 39149373 Free PMC article. Preprint.
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team; Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Shrock E, et al. Among authors: lee ih. Science. 2020 Nov 27;370(6520):eabd4250. doi: 10.1126/science.abd4250. Epub 2020 Sep 29. Science. 2020. PMID: 32994364 Free PMC article.
1,187 results