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CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ. Sarek G, et al. Among authors: chowdhury d. Nature. 2019 Nov;575(7783):523-527. doi: 10.1038/s41586-019-1744-8. Epub 2019 Nov 13. Nature. 2019. PMID: 31723267 Free PMC article.
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.
Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ. Keogh MC, et al. Among authors: chowdhury d. Nature. 2006 Jan 26;439(7075):497-501. doi: 10.1038/nature04384. Epub 2005 Nov 20. Nature. 2006. PMID: 16299494
DNA breaks and chromosome pulverization from errors in mitosis.
Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. Crasta K, et al. Among authors: chowdhury d. Nature. 2012 Jan 18;482(7383):53-8. doi: 10.1038/nature10802. Nature. 2012. PMID: 22258507 Free PMC article.
TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D. Drané P, et al. Among authors: chowdhury d. Nature. 2017 Mar 9;543(7644):211-216. doi: 10.1038/nature21358. Epub 2017 Feb 27. Nature. 2017. PMID: 28241136 Free PMC article.
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G. Botuyan MV, et al. Among authors: chowdhury d. Nat Struct Mol Biol. 2018 Jul;25(7):591-600. doi: 10.1038/s41594-018-0083-z. Epub 2018 Jul 2. Nat Struct Mol Biol. 2018. PMID: 29967538 Free PMC article.
A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1.
Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D. Zheng XF, et al. Among authors: chowdhury d. Nat Commun. 2019 Sep 18;10(1):4252. doi: 10.1038/s41467-019-12084-x. Nat Commun. 2019. PMID: 31534152 Free PMC article.
TRIP13 regulates DNA repair pathway choice through REV7 conformational change.
Clairmont CS, Sarangi P, Ponnienselvan K, Galli LD, Csete I, Moreau L, Adelmant G, Chowdhury D, Marto JA, D'Andrea AD. Clairmont CS, et al. Among authors: chowdhury d, d andrea ad. Nat Cell Biol. 2020 Jan;22(1):87-96. doi: 10.1038/s41556-019-0442-y. Epub 2020 Jan 8. Nat Cell Biol. 2020. PMID: 31915374 Free PMC article.
705 results