Luque FJ - Search Results

1

Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M.

Aragó M, Moreno-Felici J, Abás S, Rodríguez-Arévalo S, Hyroššová P, Figueras A, Viñals F, Pérez B, Loza MI, Brea J, Latorre P, Carrodeguas JA, García-Rovés PM, Galdeano C, Ginex T, Luque FJ, Escolano C, Perales JC. Aragó M, et al. Among authors: luque fj. Biomed Pharmacother. 2020 Jan;121:109601. doi: 10.1016/j.biopha.2019.109601. Epub 2019 Nov 15. Biomed Pharmacother. 2020. PMID: 31739159 Free article.

2

Conjugate additions to phenylglycinol-derived unsaturated delta-lactams. Enantioselective synthesis of uleine alkaloids.

Amat M, Pérez M, Llor N, Escolano C, Luque FJ, Molins E, Bosch J. Amat M, et al. Among authors: luque fj. J Org Chem. 2004 Dec 10;69(25):8681-93. doi: 10.1021/jo0487101. J Org Chem. 2004. PMID: 15575744

3

On the origin of the stereoselectivity in the alkylation of oxazolopiperidone enolates.

Soteras I, Lozano O, Gómez-Esqué A, Escolano C, Orozco M, Amat M, Bosch J, Luque FJ. Soteras I, et al. Among authors: luque fj. J Am Chem Soc. 2006 May 24;128(20):6581-8. doi: 10.1021/ja055393m. J Am Chem Soc. 2006. PMID: 16704257

4

Structure-directed reversion in the pi-facial stereoselective alkylation of chiral bicyclic lactams.

Soteras I, Lozano O, Escolano C, Orozco M, Amat M, Bosch J, Luque FJ. Soteras I, et al. Among authors: luque fj. J Org Chem. 2008 Oct 3;73(19):7756-63. doi: 10.1021/jo801665k. Epub 2008 Sep 3. J Org Chem. 2008. PMID: 18763825

5

First asymmetric cascade reaction catalysed by chiral primary aminoalcohols.

Arróniz C, Escolano C, Luque FJ, Bosch J, Amat M. Arróniz C, et al. Among authors: luque fj. Org Biomol Chem. 2011 Jul 21;9(14):5079-85. doi: 10.1039/c1ob05400g. Epub 2011 May 25. Org Biomol Chem. 2011. PMID: 21614385

6

First diastereoselective [3 + 2] cycloaddition reaction of diethyl isocyanomethylphosphonate and maleimides.

Arróniz C, Molina J, Abás S, Molins E, Campanera JM, Luque FJ, Escolano C. Arróniz C, et al. Among authors: luque fj. Org Biomol Chem. 2013 Feb 13;11(10):1640-9. doi: 10.1039/c3ob26766k. Org Biomol Chem. 2013. PMID: 23358611

7

Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.

Di Pietro O, Pérez-Areales FJ, Juárez-Jiménez J, Espargaró A, Clos MV, Pérez B, Lavilla R, Sabaté R, Luque FJ, Muñoz-Torrero D. Di Pietro O, et al. Among authors: luque fj. Eur J Med Chem. 2014 Sep 12;84:107-17. doi: 10.1016/j.ejmech.2014.07.021. Epub 2014 Jul 7. Eur J Med Chem. 2014. PMID: 25016233

8

Development and validation of hydrophobic molecular fields derived from the quantum mechanical IEF/PCM-MST solvation models in 3D-QSAR.

Ginex T, Muñoz-Muriedas J, Herrero E, Gibert E, Cozzini P, Luque FJ. Ginex T, et al. Among authors: luque fj. J Comput Chem. 2016 May 15;37(13):1147-62. doi: 10.1002/jcc.24305. Epub 2016 Jan 26. J Comput Chem. 2016. PMID: 26813046

9

Application of the quantum mechanical IEF/PCM-MST hydrophobic descriptors to selectivity in ligand binding.

Ginex T, Muñoz-Muriedas J, Herrero E, Gibert E, Cozzini P, Luque FJ. Ginex T, et al. Among authors: luque fj. J Mol Model. 2016 Jun;22(6):136. doi: 10.1007/s00894-016-2991-3. Epub 2016 May 17. J Mol Model. 2016. PMID: 27188723

10

Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.

Di Pietro O, Alencar N, Esteban G, Viayna E, Szałaj N, Vázquez J, Juárez-Jiménez J, Sola I, Pérez B, Solé M, Unzeta M, Muñoz-Torrero D, Luque FJ. Di Pietro O, et al. Among authors: luque fj. Bioorg Med Chem. 2016 Oct 15;24(20):4835-4854. doi: 10.1016/j.bmc.2016.06.045. Epub 2016 Jun 28. Bioorg Med Chem. 2016. PMID: 27396685

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