Kovacevic Z - Search Results

1

Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.

Park KC, Geleta B, Leck LYW, Paluncic J, Chiang S, Jansson PJ, Kovacevic Z, Richardson DR. Park KC, et al. Among authors: kovacevic z. J Biol Chem. 2020 Jan 10;295(2):481-503. doi: 10.1074/jbc.RA119.011341. Epub 2019 Nov 19. J Biol Chem. 2020. PMID: 31744884 Free PMC article.

2

The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

Chen Z, Zhang D, Yue F, Zheng M, Kovacevic Z, Richardson DR. Chen Z, et al. Among authors: kovacevic z. J Biol Chem. 2012 May 18;287(21):17016-17028. doi: 10.1074/jbc.M112.350470. Epub 2012 Mar 27. J Biol Chem. 2012. PMID: 22453918 Free PMC article.

3

The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.

Sahni S, Bae DH, Lane DJ, Kovacevic Z, Kalinowski DS, Jansson PJ, Richardson DR. Sahni S, et al. Among authors: kovacevic z. J Biol Chem. 2014 Apr 4;289(14):9692-709. doi: 10.1074/jbc.M113.529511. Epub 2014 Feb 15. J Biol Chem. 2014. PMID: 24532803 Free PMC article.

4

The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones.

Jansson PJ, Kalinowski DS, Lane DJ, Kovacevic Z, Seebacher NA, Fouani L, Sahni S, Merlot AM, Richardson DR. Jansson PJ, et al. Among authors: kovacevic z. Pharmacol Res. 2015 Oct;100:255-60. doi: 10.1016/j.phrs.2015.08.013. Epub 2015 Aug 28. Pharmacol Res. 2015. PMID: 26318762 Review.

5

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.

Kovacevic Z, Menezes SV, Sahni S, Kalinowski DS, Bae DH, Lane DJ, Richardson DR. Kovacevic Z, et al. J Biol Chem. 2016 Jan 15;291(3):1029-52. doi: 10.1074/jbc.M115.689653. Epub 2015 Nov 3. J Biol Chem. 2016. PMID: 26534963 Free PMC article.

6

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization.

Al-Eisawi Z, Stefani C, Jansson PJ, Arvind A, Sharpe PC, Basha MT, Iskander GM, Kumar N, Kovacevic Z, Lane DJ, Sahni S, Bernhardt PV, Richardson DR, Kalinowski DS. Al-Eisawi Z, et al. Among authors: kovacevic z. J Med Chem. 2016 Jan 14;59(1):294-312. doi: 10.1021/acs.jmedchem.5b01399. Epub 2015 Dec 31. J Med Chem. 2016. PMID: 26645570

7

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.

Park KC, Fouani L, Jansson PJ, Wooi D, Sahni S, Lane DJ, Palanimuthu D, Lok HC, Kovačević Z, Huang ML, Kalinowski DS, Richardson DR. Park KC, et al. Among authors: kovacevic z. Metallomics. 2016 Sep 1;8(9):874-86. doi: 10.1039/c6mt00105j. Epub 2016 Jun 23. Metallomics. 2016. PMID: 27334916 Review.

8

A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity.

Lok HC, Sahni S, Jansson PJ, Kovacevic Z, Hawkins CL, Richardson DR. Lok HC, et al. Among authors: kovacevic z. J Biol Chem. 2016 Dec 30;291(53):27042-27061. doi: 10.1074/jbc.M116.763714. Epub 2016 Nov 19. J Biol Chem. 2016. PMID: 27866158 Free PMC article.

9

Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.

Menezes SV, Sahni S, Kovacevic Z, Richardson DR. Menezes SV, et al. Among authors: kovacevic z. J Biol Chem. 2017 Aug 4;292(31):12772-12782. doi: 10.1074/jbc.R117.776393. Epub 2017 Jun 14. J Biol Chem. 2017. PMID: 28615452 Free PMC article. Review.

10

Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents.

Merlot AM, Kalinowski DS, Kovacevic Z, Jansson PJ, Sahni S, Huang ML, Lane DJR, Lok H, Richardson DR. Merlot AM, et al. Among authors: kovacevic z. Curr Med Chem. 2019;26(2):302-322. doi: 10.2174/0929867324666170705120809. Curr Med Chem. 2019. PMID: 28685681 Review.

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