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ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Mabanglo MF, Leung E, Vahidi S, Seraphim TV, Eger BT, Bryson S, Bhandari V, Zhou JL, Mao YQ, Rizzolo K, Barghash MM, Goodreid JD, Phanse S, Babu M, Barbosa LRS, Ramos CHI, Batey RA, Kay LE, Pai EF, Houry WA. Mabanglo MF, et al. Among authors: vahidi s. Commun Biol. 2019 Nov 13;2:410. doi: 10.1038/s42003-019-0656-3. eCollection 2019. Commun Biol. 2019. PMID: 31754640 Free PMC article.
Reversible inhibition of the ClpP protease via an N-terminal conformational switch.
Vahidi S, Ripstein ZA, Bonomi M, Yuwen T, Mabanglo MF, Juravsky JB, Rizzolo K, Velyvis A, Houry WA, Vendruscolo M, Rubinstein JL, Kay LE. Vahidi S, et al. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6447-E6456. doi: 10.1073/pnas.1805125115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941580 Free PMC article.
94 results