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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
Liu B, Trout REL, Chu GH, McGarry D, Jackson RW, Hamrick JC, Daigle DM, Cusick SM, Pozzi C, De Luca F, Benvenuti M, Mangani S, Docquier JD, Weiss WJ, Pevear DC, Xerri L, Burns CJ. Liu B, et al. Among authors: mangani s. J Med Chem. 2020 Mar 26;63(6):2789-2801. doi: 10.1021/acs.jmedchem.9b01518. Epub 2019 Dec 16. J Med Chem. 2020. PMID: 31765155 Free PMC article.
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates.
Docquier JD, Benvenuti M, Calderone V, Giuliani F, Kapetis D, De Luca F, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: mangani s. Antimicrob Agents Chemother. 2010 May;54(5):2167-74. doi: 10.1128/AAC.01517-09. Epub 2010 Feb 9. Antimicrob Agents Chemother. 2010. PMID: 20145076 Free PMC article.
High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.
Docquier JD, Benvenuti M, Calderone V, Stoczko M, Menciassi N, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: mangani s. Antimicrob Agents Chemother. 2010 Oct;54(10):4343-51. doi: 10.1128/AAC.00409-10. Epub 2010 Aug 9. Antimicrob Agents Chemother. 2010. PMID: 20696874 Free PMC article.
Structure of the extended-spectrum β-lactamase TEM-72 inhibited by citrate.
Docquier JD, Benvenuti M, Calderone V, Rossolini GM, Mangani S. Docquier JD, et al. Among authors: mangani s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Mar 1;67(Pt 3):303-6. doi: 10.1107/S1744309110054680. Epub 2011 Feb 18. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21393831 Free PMC article.
137 results