Trapani JA - Search Results

1

Lipid order and charge protect killer T cells from accidental death.

Rudd-Schmidt JA, Hodel AW, Noori T, Lopez JA, Cho HJ, Verschoor S, Ciccone A, Trapani JA, Hoogenboom BW, Voskoboinik I. Rudd-Schmidt JA, et al. Among authors: trapani ja. Nat Commun. 2019 Nov 27;10(1):5396. doi: 10.1038/s41467-019-13385-x. Nat Commun. 2019. PMID: 31776337 Free PMC article.

2

Functional significance of the perforin/granzyme cell death pathway.

Trapani JA, Smyth MJ. Trapani JA, et al. Nat Rev Immunol. 2002 Oct;2(10):735-47. doi: 10.1038/nri911. Nat Rev Immunol. 2002. PMID: 12360212 Review.

3

The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene.

Voskoboinik I, Thia MC, De Bono A, Browne K, Cretney E, Jackson JT, Darcy PK, Jane SM, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. J Exp Med. 2004 Sep 20;200(6):811-6. doi: 10.1084/jem.20040776. Epub 2004 Sep 14. J Exp Med. 2004. PMID: 15365097 Free PMC article.

4

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

Voskoboinik I, Thia MC, Fletcher J, Ciccone A, Browne K, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. J Biol Chem. 2005 Mar 4;280(9):8426-34. doi: 10.1074/jbc.M413303200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576364 Free article.

5

A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis.

Voskoboinik I, Thia MC, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Blood. 2005 Jun 15;105(12):4700-6. doi: 10.1182/blood-2004-12-4935. Epub 2005 Mar 8. Blood. 2005. PMID: 15755897 Free article.

6

Addressing the mysteries of perforin function.

Voskoboinik I, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Immunol Cell Biol. 2006 Feb;84(1):66-71. doi: 10.1111/j.1440-1711.2005.01409.x. Immunol Cell Biol. 2006. PMID: 16405653 Review.

7

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.

Waterhouse NJ, Sutton VR, Sedelies KA, Ciccone A, Jenkins M, Turner SJ, Bird PI, Trapani JA. Waterhouse NJ, et al. Among authors: trapani ja. J Cell Biol. 2006 Apr 10;173(1):133-44. doi: 10.1083/jcb.200510072. J Cell Biol. 2006. PMID: 16606695 Free PMC article.

8

Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells.

Baran K, Ciccone A, Peters C, Yagita H, Bird PI, Villadangos JA, Trapani JA. Baran K, et al. Among authors: trapani ja. J Biol Chem. 2006 Oct 13;281(41):30485-91. doi: 10.1074/jbc.M602007200. Epub 2006 Aug 16. J Biol Chem. 2006. PMID: 16914553 Free article.

9

Perforin-mediated target-cell death and immune homeostasis.

Voskoboinik I, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Nat Rev Immunol. 2006 Dec;6(12):940-52. doi: 10.1038/nri1983. Nat Rev Immunol. 2006. PMID: 17124515 Review.

10

Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.

Sutton VR, Waterhouse NJ, Browne KA, Sedelies K, Ciccone A, Anthony D, Koskinen A, Mullbacher A, Trapani JA. Sutton VR, et al. Among authors: trapani ja. J Cell Biol. 2007 Feb 12;176(4):425-33. doi: 10.1083/jcb.200609077. Epub 2007 Feb 5. J Cell Biol. 2007. PMID: 17283185 Free PMC article.

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