ALK phosphorylates SMAD4 on tyrosine to disable TGF-β tumour suppressor functions.
Zhang Q, Xiao M, Gu S, Xu Y, Liu T, Li H, Yu Y, Qin L, Zhu Y, Chen F, Wang Y, Ding C, Wu H, Ji H, Chen Z, Zu Y, Malkoski S, Li Y, Liang T, Ji J, Qin J, Xu P, Zhao B, Shen L, Lin X, Feng XH.
Zhang Q, et al.
Nat Cell Biol. 2019 Feb;21(2):179-189. doi: 10.1038/s41556-018-0264-3. Epub 2019 Jan 21.
Nat Cell Biol. 2019.
PMID: 30664791