Jiménez-Ruiz A - Search Results

1

Generation of endoplasmic reticulum stress and inhibition of autophagy by plitidepsin induces proteotoxic apoptosis in cancer cells.

Losada A, Berlanga JJ, Molina-Guijarro JM, Jiménez-Ruiz A, Gago F, Avilés P, de Haro C, Martínez-Leal JF. Losada A, et al. Biochem Pharmacol. 2020 Feb;172:113744. doi: 10.1016/j.bcp.2019.113744. Epub 2019 Dec 6. Biochem Pharmacol. 2020. PMID: 31812675

2

Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus.

Rico E, Alzate JF, Arias AA, Moreno D, Clos J, Gago F, Moreno I, Domínguez M, Jiménez-Ruiz A. Rico E, et al. Mol Biochem Parasitol. 2009 Jan;163(1):28-38. doi: 10.1016/j.molbiopara.2008.09.007. Epub 2008 Oct 2. Mol Biochem Parasitol. 2009. PMID: 18940204

3

Protein-protein interactions at an enzyme-substrate interface: characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli thioredoxin reductase.

Negri A, Rodríguez-Larrea D, Marco E, Jiménez-Ruiz A, Sánchez-Ruiz JM, Gago F. Negri A, et al. Proteins. 2010 Jan;78(1):36-51. doi: 10.1002/prot.22490. Proteins. 2010. PMID: 19585660

4

Mechanistic insight into the catalytic activity of ββα-metallonucleases from computer simulations: Vibrio vulnificus periplasmic nuclease as a test case.

Bueren-Calabuig JA, Coderch C, Rico E, Jiménez-Ruiz A, Gago F. Bueren-Calabuig JA, et al. Chembiochem. 2011 Nov 25;12(17):2615-22. doi: 10.1002/cbic.201100485. Epub 2011 Oct 6. Chembiochem. 2011. PMID: 22114054

5

5'-Trityl-substituted thymidine derivatives as a novel class of antileishmanial agents: Leishmania infantum EndoG as a potential target.

Casanova E, Moreno D, Gigante A, Rico E, Genes CM, Oliva C, Camarasa MJ, Gago F, Jiménez-Ruiz A, Pérez-Pérez MJ. Casanova E, et al. ChemMedChem. 2013 Jul;8(7):1161-74. doi: 10.1002/cmdc.201300129. Epub 2013 Apr 26. ChemMedChem. 2013. PMID: 23625887

6

Probing the dimerization interface of Leishmania infantum trypanothione reductase with site-directed mutagenesis and short peptides.

Toro MA, Sánchez-Murcia PA, Moreno D, Ruiz-Santaquiteria M, Alzate JF, Negri A, Camarasa MJ, Gago F, Velázquez S, Jiménez-Ruiz A. Toro MA, et al. Chembiochem. 2013 Jul 8;14(10):1212-7. doi: 10.1002/cbic.201200744. Epub 2013 Jun 6. Chembiochem. 2013. PMID: 23744811

7

Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.

Rico E, Oliva C, Gutierrez KJ, Alzate JF, Genes CM, Moreno D, Casanova E, Gigante A, Pérez-Pérez MJ, Camarasa MJ, Clos J, Gago F, Jiménez-Ruiz A. Rico E, et al. PLoS One. 2014 Feb 26;9(2):e89526. doi: 10.1371/journal.pone.0089526. eCollection 2014. PLoS One. 2014. PMID: 24651293 Free PMC article.

8

Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania.

Genes CM, de Lucio H, Sánchez-Murcia PA, Gago F, Jiménez-Ruiz A. Genes CM, et al. Cell Death Dis. 2016 Jul 28;7(7):e2318. doi: 10.1038/cddis.2016.229. Cell Death Dis. 2016. PMID: 27468694 Free PMC article. No abstract available.

9

A functional BH3 domain in an aquaporin from Leishmania infantum.

Genes CM, de Lucio H, González VM, Sánchez-Murcia PA, Rico E, Gago F, Fasel N, Jiménez-Ruiz A. Genes CM, et al. Cell Death Discov. 2016 Jul 4;2:16043. doi: 10.1038/cddiscovery.2016.43. eCollection 2016. Cell Death Discov. 2016. PMID: 27551533 Free PMC article.

10

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity.

Ruiz-Santaquiteria M, Sánchez-Murcia PA, Toro MA, de Lucio H, Gutiérrez KJ, de Castro S, Carneiro FAC, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Ruiz-Santaquiteria M, et al. Eur J Med Chem. 2017 Jul 28;135:49-59. doi: 10.1016/j.ejmech.2017.04.020. Epub 2017 Apr 13. Eur J Med Chem. 2017. PMID: 28431354 Free article.

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