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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Krivtsov AV, Evans K, Gadrey JY, Eschle BK, Hatton C, Uckelmann HJ, Ross KN, Perner F, Olsen SN, Pritchard T, McDermott L, Jones CD, Jing D, Braytee A, Chacon D, Earley E, McKeever BM, Claremon D, Gifford AJ, Lee HJ, Teicher BA, Pimanda JE, Beck D, Perry JA, Smith MA, McGeehan GM, Lock RB, Armstrong SA. Krivtsov AV, et al. Among authors: chacon d. Cancer Cell. 2019 Dec 9;36(6):660-673.e11. doi: 10.1016/j.ccell.2019.11.001. Cancer Cell. 2019. PMID: 31821784 Free PMC article.
Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.
Thoms JAI, Truong P, Subramanian S, Knezevic K, Harvey G, Huang Y, Seneviratne JA, Carter DR, Joshi S, Skhinas J, Chacon D, Shah A, de Jong I, Beck D, Göttgens B, Larsson J, Wong JWH, Zanini F, Pimanda JE. Thoms JAI, et al. Among authors: chacon d. Blood. 2021 Oct 21;138(16):1441-1455. doi: 10.1182/blood.2020009707. Blood. 2021. PMID: 34075404 Free article.
Shared roles for Scl and Lyl1 in murine platelet production and function.
Chiu SK, Orive SL, Moon MJ, Saw J, Ellis S, Kile BT, Huang Y, Chacon D, Pimanda JE, Beck D, Hamilton JR, Tremblay CS, Curtis DJ. Chiu SK, et al. Among authors: chacon d. Blood. 2019 Sep 5;134(10):826-835. doi: 10.1182/blood.2019896175. Epub 2019 Jul 12. Blood. 2019. PMID: 31300405 Free article.
A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.
Beck D, Thoms JAI, Palu C, Herold T, Shah A, Olivier J, Boelen L, Huang Y, Chacon D, Brown A, Babic M, Hahn C, Perugini M, Zhou X, Huntly BJ, Schwarzer A, Klusmann JH, Berdel WE, Wörmann B, Büchner T, Hiddemann W, Bohlander SK, To LB, Scott HS, Lewis ID, D'Andrea RJ, Wong JWH, Pimanda JE. Beck D, et al. Among authors: chacon d, d andrea rj. Leukemia. 2018 Feb;32(2):263-272. doi: 10.1038/leu.2017.210. Epub 2017 Jul 4. Leukemia. 2018. PMID: 28674423
OncoCis: annotation of cis-regulatory mutations in cancer.
Perera D, Chacon D, Thoms JA, Poulos RC, Shlien A, Beck D, Campbell PJ, Pimanda JE, Wong JW. Perera D, et al. Among authors: chacon d. Genome Biol. 2014;15(10):485. doi: 10.1186/s13059-014-0485-0. Genome Biol. 2014. PMID: 25298093 Free PMC article.
Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.
Chandrakanthan V, Rorimpandey P, Zanini F, Chacon D, Olivier J, Joshi S, Kang YC, Knezevic K, Huang Y, Qiao Q, Oliver RA, Unnikrishnan A, Carter DR, Lee B, Brownlee C, Power C, Brink R, Mendez-Ferrer S, Enikolopov G, Walsh W, Göttgens B, Taoudi S, Beck D, Pimanda JE. Chandrakanthan V, et al. Among authors: chacon d. Nat Cell Biol. 2022 Aug;24(8):1211-1225. doi: 10.1038/s41556-022-00955-3. Epub 2022 Jul 28. Nat Cell Biol. 2022. PMID: 35902769 Free PMC article.
Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine.
Yeola A, Subramanian S, Oliver RA, Lucas CA, Thoms JAI, Yan F, Olivier J, Chacon D, Tursky ML, Srivastava P, Potas JR, Hung T, Power C, Hardy P, Ma DD, Kilian KA, McCarroll J, Kavallaris M, Hesson LB, Beck D, Curtis DJ, Wong JWH, Hardeman EC, Walsh WR, Mobbs R, Chandrakanthan V, Pimanda JE. Yeola A, et al. Among authors: chacon d. Sci Adv. 2021 Jan 13;7(3):eabd1929. doi: 10.1126/sciadv.abd1929. Print 2021 Jan. Sci Adv. 2021. PMID: 33523875 Free PMC article.
RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.
Guo D, Lui GYL, Lai SL, Wilmott JS, Tikoo S, Jackett LA, Quek C, Brown DL, Sharp DM, Kwan RYQ, Chacon D, Wong JH, Beck D, van Geldermalsen M, Holst J, Thompson JF, Mann GJ, Scolyer RA, Stow JL, Weninger W, Haass NK, Beaumont KA. Guo D, et al. Among authors: chacon d. Int J Cancer. 2019 Jun 15;144(12):3070-3085. doi: 10.1002/ijc.32064. Epub 2019 Jan 3. Int J Cancer. 2019. PMID: 30556600
88 results