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Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action.
Laselva O, Eckford PD, Bartlett C, Ouyang H, Gunawardena TN, Gonska T, Moraes TJ, Bear CE. Laselva O, et al. Among authors: eckford pd. J Cyst Fibros. 2020 Sep;19(5):717-727. doi: 10.1016/j.jcf.2019.12.001. Epub 2019 Dec 9. J Cyst Fibros. 2020. PMID: 31831337 Free article.
Structural basis for alginate secretion across the bacterial outer membrane.
Whitney JC, Hay ID, Li C, Eckford PD, Robinson H, Amaya MF, Wood LF, Ohman DE, Bear CE, Rehm BH, Howell PL. Whitney JC, et al. Among authors: eckford pd. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13083-8. doi: 10.1073/pnas.1104984108. Epub 2011 Jul 21. Proc Natl Acad Sci U S A. 2011. PMID: 21778407 Free PMC article.
Functional Rescue of F508del-CFTR Using Small Molecule Correctors.
Molinski S, Eckford PD, Pasyk S, Ahmadi S, Chin S, Bear CE. Molinski S, et al. Among authors: eckford pd. Front Pharmacol. 2012 Sep 26;3:160. doi: 10.3389/fphar.2012.00160. eCollection 2012. Front Pharmacol. 2012. PMID: 23055971 Free PMC article.
31 results