Xu H - Search Results

1

Design and synthesis of boron-containing diphenylpyrimidines as potent BTK and JAK3 dual inhibitors.

Ren J, Shi W, Zhao D, Wang Q, Chang X, He X, Wang X, Gao Y, Lu P, Zhang X, Xu H, Zhang Y. Ren J, et al. Among authors: xu h. Bioorg Med Chem. 2020 Jan 15;28(2):115236. doi: 10.1016/j.bmc.2019.115236. Epub 2019 Nov 30. Bioorg Med Chem. 2020. PMID: 31843459

2

The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes.

Deng J, Peng L, Zhang G, Lan X, Li C, Chen F, Zhou Y, Lin Z, Chen L, Dai R, Xu H, Yang L, Zhang X, Hu W. Deng J, et al. Among authors: xu h. Eur J Med Chem. 2011 Jan;46(1):71-6. doi: 10.1016/j.ejmech.2010.10.016. Epub 2010 Oct 26. Eur J Med Chem. 2011. PMID: 21106276

3

Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization.

Xie H, Zeng L, Zeng S, Lu X, Zhang G, Zhao X, Cheng N, Tu Z, Li Z, Xu H, Yang L, Zhang X, Huang M, Zhao J, Hu W. Xie H, et al. Among authors: xu h. Eur J Med Chem. 2012 Jun;52:205-12. doi: 10.1016/j.ejmech.2012.03.015. Epub 2012 Mar 17. Eur J Med Chem. 2012. PMID: 22475866

4

Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization.

Zeng S, Xie H, Zeng LL, Lu X, Zhao X, Zhang GC, Tu ZC, Xu HJ, Yang L, Zhang XQ, Hu W. Zeng S, et al. Among authors: xu hj. Bioorg Med Chem. 2013 Apr 1;21(7):1749-55. doi: 10.1016/j.bmc.2013.01.062. Epub 2013 Feb 8. Bioorg Med Chem. 2013. PMID: 23434133

5

Highly potent dipeptidyl peptidase IV inhibitors derived from Alogliptin through pharmacophore hybridization and lead optimization.

Xie H, Zeng L, Zeng S, Lu X, Zhao X, Zhang G, Tu Z, Xu H, Yang L, Zhang X, Wang S, Hu W. Xie H, et al. Among authors: xu h. Eur J Med Chem. 2013 Oct;68:312-20. doi: 10.1016/j.ejmech.2013.08.010. Epub 2013 Aug 13. Eur J Med Chem. 2013. PMID: 23994324

6

C-Aryl glucoside SGLT2 inhibitors containing a biphenyl motif as potential anti-diabetic agents.

Ding Y, Mao L, Xu D, Xie H, Yang L, Xu H, Geng W, Gao Y, Xia C, Zhang X, Meng Q, Wu D, Zhao J, Hu W. Ding Y, et al. Among authors: xu d, xu h. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2744-8. doi: 10.1016/j.bmcl.2015.05.040. Epub 2015 May 27. Bioorg Med Chem Lett. 2015. PMID: 26026363

7

Validated UPLC/MS/MS assay for quantitative bioanalysis of elbasvir in rat plasma and application to pharmacokinetic study.

Liu H, Xu H, Song W, Zhang Y, Yu S, Huang X. Liu H, et al. Among authors: xu h. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:150-156. doi: 10.1016/j.jchromb.2016.02.025. Epub 2016 Feb 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26927874

8

Rapid generation of a novel DPP-4 inhibitor with long-acting properties: SAR study and PK/PD evaluation.

Xie H, Zeng S, He Y, Zhang G, Yu P, Zhong G, Xu H, Yang L, Wang S, Zhao X, Hu W. Xie H, et al. Among authors: xu h. Eur J Med Chem. 2017 Dec 1;141:519-529. doi: 10.1016/j.ejmech.2017.10.029. Epub 2017 Oct 12. Eur J Med Chem. 2017. PMID: 29078995

9

6,7-Dimorpholinoalkoxy quinazoline derivatives as potent EGFR inhibitors with enhanced antiproliferative activities against tumor cells.

Zhang Y, Chen L, Xu H, Li X, Zhao L, Wang W, Li B, Zhang X. Zhang Y, et al. Among authors: xu h. Eur J Med Chem. 2018 Mar 10;147:77-89. doi: 10.1016/j.ejmech.2018.01.090. Epub 2018 Feb 1. Eur J Med Chem. 2018. PMID: 29421573

10

Design, synthesis and identification of silicon-containing HCV NS5A inhibitors with pan-genotype activity.

Liu B, Gai K, Qin H, Liu X, Cao Y, Lu Q, Lu D, Chen D, Shen H, Song W, Zhang Y, Wang X, Xu H, Zhang Y. Liu B, et al. Among authors: xu h. Eur J Med Chem. 2018 Mar 25;148:95-105. doi: 10.1016/j.ejmech.2018.02.025. Epub 2018 Feb 10. Eur J Med Chem. 2018. PMID: 29454920

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

45,057 results

Search Page

Filters