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LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.
Tang F, Gao R, Jeevan-Raj B, Wyss CB, Kalathur RKR, Piscuoglio S, Ng CKY, Hindupur SK, Nuciforo S, Dazert E, Bock T, Song S, Buechel D, Morini MF, Hergovich A, Matthias P, Lim DS, Terracciano LM, Heim MH, Hall MN, Christofori G. Tang F, et al. Among authors: christofori g. Nat Commun. 2019 Dec 17;10(1):5755. doi: 10.1038/s41467-019-13591-7. Nat Commun. 2019. PMID: 31848340 Free PMC article.
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis.
Gao R, Buechel D, Kalathur RKR, Morini MF, Coto-Llerena M, Ercan C, Piscuoglio S, Chen Q, Blumer T, Wang X, Dazert E, Heim MH, Hall MN, Tang F, Christofori G. Gao R, et al. Among authors: christofori g. Oncogenesis. 2021 Jul 16;10(7):52. doi: 10.1038/s41389-021-00338-7. Oncogenesis. 2021. PMID: 34272356 Free PMC article.
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members.
Coto-Llerena M, Tosti N, Taha-Mehlitz S, Kancherla V, Paradiso V, Gallon J, Bianco G, Garofoli A, Ghosh S, Tang F, Ercan C, Christofori GM, Matter MS, Droeser RA, Zavolan M, Soysal SD, von Flüe M, Kollmar O, Terracciano LM, Ng CKY, Piscuoglio S. Coto-Llerena M, et al. Among authors: christofori gm. Hepatol Commun. 2021 Jan 20;5(4):661-674. doi: 10.1002/hep4.1656. eCollection 2021 Apr. Hepatol Commun. 2021. PMID: 33860124 Free PMC article.
A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer.
Saxena M, Kalathur RKR, Rubinstein N, Vettiger A, Sugiyama N, Neutzner M, Coto-Llerena M, Kancherla V, Ercan C, Piscuoglio S, Fischer J, Fagiani E, Cantù C, Basler K, Christofori G. Saxena M, et al. Among authors: christofori g. Cancer Res. 2020 Sep 1;80(17):3631-3648. doi: 10.1158/0008-5472.CAN-19-2910. Epub 2020 Jun 25. Cancer Res. 2020. PMID: 32586983
179 results