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Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
Wheeler JM, McMillan P, Strovas TJ, Liachko NF, Amlie-Wolf A, Kow RL, Klein RL, Szot P, Robinson L, Guthrie C, Saxton A, Kanaan NM, Raskind M, Peskind E, Trojanowski JQ, Lee VMY, Wang LS, Keene CD, Bird T, Schellenberg GD, Kraemer B. Wheeler JM, et al. Among authors: robinson l. Sci Transl Med. 2019 Dec 18;11(523):eaao6545. doi: 10.1126/scitranslmed.aao6545. Sci Transl Med. 2019. PMID: 31852801 Free PMC article.
High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration.
Wheeler JM, McMillan PJ, Hawk M, Iba M, Robinson L, Xu GJ, Dombroski BA, Jeong D, Dichter MA, Juul H, Loomis E, Raskind M, Leverenz JB, Trojanowski JQ, Lee VM, Schellenberg GD, Kraemer BC. Wheeler JM, et al. Among authors: robinson l. Acta Neuropathol Commun. 2015 Jun 4;3:33. doi: 10.1186/s40478-015-0210-6. Acta Neuropathol Commun. 2015. PMID: 26041339 Free PMC article.
Tau isoform regulation is region- and cell-specific in mouse brain.
McMillan P, Korvatska E, Poorkaj P, Evstafjeva Z, Robinson L, Greenup L, Leverenz J, Schellenberg GD, D'Souza I. McMillan P, et al. Among authors: robinson l. J Comp Neurol. 2008 Dec 20;511(6):788-803. doi: 10.1002/cne.21867. J Comp Neurol. 2008. PMID: 18925637 Free PMC article.
Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to murine brain.
Ediriweera GR, Sivaram AJ, Cowin G, Brown M, McAlary L, Lum JS, Fletcher NL, Robinson L, Simpson JD, Chen L, Wasielewska JM, Byrne E, Finnie JW, Manavis J, White AR, Yerbury JJ, Thurecht KJ, Vine KL. Ediriweera GR, et al. Among authors: robinson l. J Control Release. 2024 Dec 5:S0168-3659(24)00833-2. doi: 10.1016/j.jconrel.2024.11.074. Online ahead of print. J Control Release. 2024. PMID: 39645085
2,996 results