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A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, Sandoval-Romero ML, Li S, Souter MNT, Eckle SBG, Corbett AJ, Reid HH, Liu L, Fairlie DP, Giles EM, Westall GP, Tothill RW, Davey MS, Berry R, Tiganis T, McCluskey J, Pellicci DG, Purcell AW, Uldrich AP, Godfrey DI, Rossjohn J. Le Nours J, et al. Among authors: liu l. Science. 2019 Dec 20;366(6472):1522-1527. doi: 10.1126/science.aav3900. Science. 2019. PMID: 31857486
Inhibitors selective for HDAC6 in enzymes and cells.
Gupta PK, Reid RC, Liu L, Lucke AJ, Broomfield SA, Andrews MR, Sweet MJ, Fairlie DP. Gupta PK, et al. Among authors: liu l. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7067-70. doi: 10.1016/j.bmcl.2010.09.100. Epub 2010 Oct 12. Bioorg Med Chem Lett. 2010. PMID: 20947351
MR1 presents microbial vitamin B metabolites to MAIT cells.
Kjer-Nielsen L, Patel O, Corbett AJ, Le Nours J, Meehan B, Liu L, Bhati M, Chen Z, Kostenko L, Reantragoon R, Williamson NA, Purcell AW, Dudek NL, McConville MJ, O'Hair RA, Khairallah GN, Godfrey DI, Fairlie DP, Rossjohn J, McCluskey J. Kjer-Nielsen L, et al. Among authors: liu l. Nature. 2012 Nov 29;491(7426):717-23. doi: 10.1038/nature11605. Epub 2012 Oct 10. Nature. 2012. PMID: 23051753
PAR2-induced inflammatory responses in human kidney tubular epithelial cells.
Vesey DA, Suen JY, Seow V, Lohman RJ, Liu L, Gobe GC, Johnson DW, Fairlie DP. Vesey DA, et al. Among authors: liu l. Am J Physiol Renal Physiol. 2013 Mar 15;304(6):F737-50. doi: 10.1152/ajprenal.00540.2012. Epub 2013 Jan 2. Am J Physiol Renal Physiol. 2013. PMID: 23283995 Free article.
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Patel O, Kjer-Nielsen L, Le Nours J, Eckle SB, Birkinshaw R, Beddoe T, Corbett AJ, Liu L, Miles JJ, Meehan B, Reantragoon R, Sandoval-Romero ML, Sullivan LC, Brooks AG, Chen Z, Fairlie DP, McCluskey J, Rossjohn J. Patel O, et al. Among authors: liu l. Nat Commun. 2013;4:2142. doi: 10.1038/ncomms3142. Nat Commun. 2013. PMID: 23846752 Free article.
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
Reantragoon R, Corbett AJ, Sakala IG, Gherardin NA, Furness JB, Chen Z, Eckle SB, Uldrich AP, Birkinshaw RW, Patel O, Kostenko L, Meehan B, Kedzierska K, Liu L, Fairlie DP, Hansen TH, Godfrey DI, Rossjohn J, McCluskey J, Kjer-Nielsen L. Reantragoon R, et al. Among authors: liu l. J Exp Med. 2013 Oct 21;210(11):2305-20. doi: 10.1084/jem.20130958. Epub 2013 Oct 7. J Exp Med. 2013. PMID: 24101382 Free PMC article.
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