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A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, Hartwig J, Irvine DJ, Luscinskas FW, Geha RS. Janssen E, et al. Among authors: tohme m. J Clin Invest. 2016 Oct 3;126(10):3837-3851. doi: 10.1172/JCI85774. Epub 2016 Sep 6. J Clin Invest. 2016. PMID: 27599296 Free PMC article.
IRAP+ endosomes restrict TLR9 activation and signaling.
Babdor J, Descamps D, Adiko AC, Tohmé M, Maschalidi S, Evnouchidou I, Vasconcellos LR, De Luca M, Mauvais FX, Garfa-Traore M, Brinkmann MM, Chignard M, Manoury B, Saveanu L. Babdor J, et al. Among authors: tohme m. Nat Immunol. 2017 May;18(5):509-518. doi: 10.1038/ni.3711. Epub 2017 Mar 20. Nat Immunol. 2017. PMID: 28319098 Free article.
Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.
Descamps D, Le Gars M, Balloy V, Barbier D, Maschalidi S, Tohme M, Chignard M, Ramphal R, Manoury B, Sallenave JM. Descamps D, et al. Among authors: tohme m. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1619-24. doi: 10.1073/pnas.1108464109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307620 Free PMC article.
47 results