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Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies.
Huyghe L, Van Parys A, Cauwels A, Van Lint S, De Munter S, Bultinck J, Zabeau L, Hostens J, Goethals A, Vanderroost N, Verhee A, Uzé G, Kley N, Peelman F, Vandekerckhove B, Brouckaert P, Tavernier J. Huyghe L, et al. Among authors: vandekerckhove b. EMBO Mol Med. 2020 Feb 7;12(2):e11223. doi: 10.15252/emmm.201911223. Epub 2020 Jan 8. EMBO Mol Med. 2020. PMID: 31912630 Free PMC article.
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Van Caeneghem Y, et al. Among authors: vandekerckhove b. Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017. Oncoimmunology. 2017. PMID: 28405508 Free PMC article.
Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.
Cauwels A, Van Lint S, Paul F, Garcin G, De Koker S, Van Parys A, Wueest T, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, Rogge E, Verhee A, Vandekerckhove B, Kley N, Uzé G, Tavernier J. Cauwels A, et al. Among authors: vandekerckhove b. Cancer Res. 2018 Jan 15;78(2):463-474. doi: 10.1158/0008-5472.CAN-17-1980. Epub 2017 Nov 29. Cancer Res. 2018. PMID: 29187401
Nanobody Based Dual Specific CARs.
De Munter S, Ingels J, Goetgeluk G, Bonte S, Pille M, Weening K, Kerre T, Abken H, Vandekerckhove B. De Munter S, et al. Among authors: vandekerckhove b. Int J Mol Sci. 2018 Jan 30;19(2):403. doi: 10.3390/ijms19020403. Int J Mol Sci. 2018. PMID: 29385713 Free PMC article.
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly.
De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, Vandekerckhove B. De Munter S, et al. Among authors: vandekerckhove b. Int J Mol Sci. 2020 Jan 30;21(3):883. doi: 10.3390/ijms21030883. Int J Mol Sci. 2020. PMID: 32019116 Free PMC article.
Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.
Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, Kerre T, Taghon T, Leclercq G, Vandekerckhove B. Billiet L, et al. Among authors: vandekerckhove b. Int J Mol Sci. 2020 Nov 20;21(22):8785. doi: 10.3390/ijms21228785. Int J Mol Sci. 2020. PMID: 33233766 Free PMC article.
Dendritic Cell-Based Immunotherapy in Lung Cancer.
Stevens D, Ingels J, Van Lint S, Vandekerckhove B, Vermaelen K. Stevens D, et al. Among authors: vandekerckhove b. Front Immunol. 2021 Feb 12;11:620374. doi: 10.3389/fimmu.2020.620374. eCollection 2020. Front Immunol. 2021. PMID: 33679709 Free PMC article. Review.
Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation.
Raes L, Stremersch S, Fraire JC, Brans T, Goetgeluk G, De Munter S, Van Hoecke L, Verbeke R, Van Hoeck J, Xiong R, Saelens X, Vandekerckhove B, De Smedt S, Raemdonck K, Braeckmans K. Raes L, et al. Among authors: vandekerckhove b. Nanomicro Lett. 2020 Sep 27;12(1):185. doi: 10.1007/s40820-020-00523-0. Nanomicro Lett. 2020. PMID: 34138203 Free PMC article.
In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality.
Bonte S, de Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, Pille M, de Cock L, Weening K, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. Bonte S, et al. Among authors: vandekerckhove b. Oncoimmunology. 2021 Jul 25;10(1):1954800. doi: 10.1080/2162402X.2021.1954800. eCollection 2021. Oncoimmunology. 2021. PMID: 34367734 Free PMC article.
165 results