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Advancing RAS/RASopathy therapies: An NCI-sponsored intramural and extramural collaboration for the study of RASopathies.
Gross AM, Frone M, Gripp KW, Gelb BD, Schoyer L, Schill L, Stronach B, Biesecker LG, Esposito D, Hernandez ER, Legius E, Loh ML, Martin S, Morrison DK, Rauen KA, Wolters PL, Zand D, McCormick F, Savage SA, Stewart DR, Widemann BC, Yohe ME. Gross AM, et al. Among authors: morrison dk. Am J Med Genet A. 2020 Apr;182(4):866-876. doi: 10.1002/ajmg.a.61485. Epub 2020 Jan 8. Am J Med Genet A. 2020. PMID: 31913576 Free PMC article.
Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.
Kowalczyk JT, Wan X, Hernandez ER, Luo R, Lyons GC, Wilson KM, Gallardo DC, Isanogle KA, Robinson CM, Mendoza A, Heske CM, Chen JQ, Luo X, Kelly AE, Difilippantinio S, Robey RW, Thomas CJ, Sackett DL, Morrison DK, Randazzo PA, Jenkins LMM, Yohe ME. Kowalczyk JT, et al. Among authors: morrison dk. Mol Cancer Ther. 2021 Feb;20(2):307-319. doi: 10.1158/1535-7163.MCT-20-0525. Epub 2020 Nov 6. Mol Cancer Ther. 2021. PMID: 33158997 Free PMC article.
Tolypocladamides A-G: Cytotoxic Peptaibols from Tolypocladium inflatum.
Senadeera SPD, Wang D, Kim CK, Smith EA, Durrant DE, Alexander PA, Wendt KL, Stephen AG, Morrison DK, Cichewicz RH, Henrich CJ, Beutler JA. Senadeera SPD, et al. Among authors: morrison dk. J Nat Prod. 2022 Jun 24;85(6):1603-1616. doi: 10.1021/acs.jnatprod.2c00240. Epub 2022 Jun 13. J Nat Prod. 2022. PMID: 35696348 Free PMC article. Review.
Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Murphy BM, Terrell EM, Chirasani VR, Weiss TJ, Lew RE, Holderbaum AM, Dhakal A, Posada V, Fort M, Bodnar MS, Carey LM, Chen M, Burd CJ, Coppola V, Morrison DK, Campbell SL, Burd CE. Murphy BM, et al. Among authors: morrison dk. Nat Commun. 2022 Jun 7;13(1):3153. doi: 10.1038/s41467-022-30881-9. Nat Commun. 2022. PMID: 35672316 Free PMC article.
Regulation of GTPase function by autophosphorylation.
Johnson CW, Seo HS, Terrell EM, Yang MH, KleinJan F, Gebregiworgis T, Gasmi-Seabrook GMC, Geffken EA, Lakhani J, Song K, Bashyal P, Popow O, Paulo JA, Liu A, Mattos C, Marshall CB, Ikura M, Morrison DK, Dhe-Paganon S, Haigis KM. Johnson CW, et al. Among authors: morrison dk. Mol Cell. 2022 Mar 3;82(5):950-968.e14. doi: 10.1016/j.molcel.2022.02.011. Epub 2022 Feb 23. Mol Cell. 2022. PMID: 35202574 Free PMC article.
123 results