Vanhaesebroeck B - Search Results

1

PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis.

Wu W, Zhou G, Han H, Huang X, Jiang H, Mukai S, Kazlauskas A, Cui J, Matsubara JA, Vanhaesebroeck B, Xia X, Wang J, Lei H. Wu W, et al. Among authors: vanhaesebroeck b. Diabetes. 2020 Apr;69(4):736-748. doi: 10.2337/db19-0713. Epub 2020 Jan 8. Diabetes. 2020. PMID: 31915155 Free PMC article.

2

Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation.

Vanhaesebroeck B, Burke JE, Madsen RR. Vanhaesebroeck B, et al. Cancer Discov. 2022 Jan;12(1):20-22. doi: 10.1158/2159-8290.CD-21-1411. Cancer Discov. 2022. PMID: 35022207 Free PMC article.

3

Idelalisib inhibits experimental proliferative vitroretinopathy.

Dong L, Han H, Huang X, Ma G, Fang D, Qi H, Han Z, Wang L, Tian J, Vanhaesebroeck B, Zhang G, Zhang S, Lei H. Dong L, et al. Among authors: vanhaesebroeck b. Lab Invest. 2022 Dec;102(12):1296-1303. doi: 10.1038/s41374-022-00822-7. Epub 2022 Jul 19. Lab Invest. 2022. PMID: 35854067 Free article.

4

NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells.

Han H, Yang Y, Han Z, Wang L, Dong L, Qi H, Liu B, Tian J, Vanhaesebroeck B, Kazlauskas A, Zhang G, Zhang S, Lei H. Han H, et al. Among authors: vanhaesebroeck b. Cells. 2023 Jan 4;12(2):207. doi: 10.3390/cells12020207. Cells. 2023. PMID: 36672142 Free PMC article.

5

Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?

Geering B, Cutillas PR, Vanhaesebroeck B. Geering B, et al. Among authors: vanhaesebroeck b. Biochem Soc Trans. 2007 Apr;35(Pt 2):199-203. doi: 10.1042/BST0350199. Biochem Soc Trans. 2007. PMID: 17371237 Review.

6

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

Graupera M, Guillermet-Guibert J, Foukas LC, Phng LK, Cain RJ, Salpekar A, Pearce W, Meek S, Millan J, Cutillas PR, Smith AJ, Ridley AJ, Ruhrberg C, Gerhardt H, Vanhaesebroeck B. Graupera M, et al. Among authors: vanhaesebroeck b. Nature. 2008 May 29;453(7195):662-6. doi: 10.1038/nature06892. Epub 2008 Apr 30. Nature. 2008. PMID: 18449193

7

Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses.

Durand CA, Hartvigsen K, Fogelstrand L, Kim S, Iritani S, Vanhaesebroeck B, Witztum JL, Puri KD, Gold MR. Durand CA, et al. Among authors: vanhaesebroeck b. J Immunol. 2009 Nov 1;183(9):5673-84. doi: 10.4049/jimmunol.0900432. J Immunol. 2009. PMID: 19843950

8

Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter.

Whitehead MA, Bombardieri M, Pitzalis C, Vanhaesebroeck B. Whitehead MA, et al. Among authors: vanhaesebroeck b. Biochem J. 2012 May 1;443(3):857-67. doi: 10.1042/BJ20112214. Biochem J. 2012. PMID: 22375552 Free PMC article.

9

Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.

Blair TA, Moore SF, Williams CM, Poole AW, Vanhaesebroeck B, Hers I. Blair TA, et al. Among authors: vanhaesebroeck b. Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1681-8. doi: 10.1161/ATVBAHA.114.303954. Epub 2014 Jun 5. Arterioscler Thromb Vasc Biol. 2014. PMID: 24903091

10

Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy.

Haddad G, Zhabyeyev P, Farhan M, Zhu LF, Kassiri Z, Rayner DC, Vanhaesebroeck B, Oudit GY, Murray AG. Haddad G, et al. Among authors: vanhaesebroeck b. Blood. 2014 Sep 25;124(13):2142-9. doi: 10.1182/blood-2014-02-557975. Epub 2014 Aug 18. Blood. 2014. PMID: 25139353 Free article.

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