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Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps.
Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, Nakasone ES, Hearn SA, Küttner V, Qiu J, Almeida AS, Perurena N, Kessenbrock K, Goldberg MS, Egeblad M. Park J, et al. Among authors: egeblad m. Sci Transl Med. 2016 Oct 19;8(361):361ra138. doi: 10.1126/scitranslmed.aag1711. Sci Transl Med. 2016. PMID: 27798263 Free PMC article.
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.
Albrengues J, Shields MA, Ng D, Park CG, Ambrico A, Poindexter ME, Upadhyay P, Uyeminami DL, Pommier A, Küttner V, Bružas E, Maiorino L, Bautista C, Carmona EM, Gimotty PA, Fearon DT, Chang K, Lyons SK, Pinkerton KE, Trotman LC, Goldberg MS, Yeh JT, Egeblad M. Albrengues J, et al. Among authors: egeblad m. Science. 2018 Sep 28;361(6409):eaao4227. doi: 10.1126/science.aao4227. Science. 2018. PMID: 30262472 Free PMC article.
Targeting potential drivers of COVID-19: Neutrophil extracellular traps.
Barnes BJ, Adrover JM, Baxter-Stoltzfus A, Borczuk A, Cools-Lartigue J, Crawford JM, Daßler-Plenker J, Guerci P, Huynh C, Knight JS, Loda M, Looney MR, McAllister F, Rayes R, Renaud S, Rousseau S, Salvatore S, Schwartz RE, Spicer JD, Yost CC, Weber A, Zuo Y, Egeblad M. Barnes BJ, et al. Among authors: egeblad m. J Exp Med. 2020 Jun 1;217(6):e20200652. doi: 10.1084/jem.20200652. J Exp Med. 2020. PMID: 32302401 Free PMC article.
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation.
Somerville TD, Biffi G, Daßler-Plenker J, Hur SK, He XY, Vance KE, Miyabayashi K, Xu Y, Maia-Silva D, Klingbeil O, Demerdash OE, Preall JB, Hollingsworth MA, Egeblad M, Tuveson DA, Vakoc CR. Somerville TD, et al. Among authors: egeblad m. Elife. 2020 Apr 24;9:e53381. doi: 10.7554/eLife.53381. Elife. 2020. PMID: 32329713 Free PMC article.
Innate Immunity and Cancer Pathophysiology.
Maiorino L, Daßler-Plenker J, Sun L, Egeblad M. Maiorino L, et al. Among authors: egeblad m. Annu Rev Pathol. 2022 Jan 24;17:425-457. doi: 10.1146/annurev-pathmechdis-032221-115501. Epub 2021 Nov 17. Annu Rev Pathol. 2022. PMID: 34788549 Free PMC article. Review.
Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection.
Adrover JM, Carrau L, Daßler-Plenker J, Bram Y, Chandar V, Houghton S, Redmond D, Merrill JR, Shevik M, tenOever BR, Lyons SK, Schwartz RE, Egeblad M. Adrover JM, et al. Among authors: egeblad m. JCI Insight. 2022 Mar 8;7(5):e157342. doi: 10.1172/jci.insight.157342. JCI Insight. 2022. PMID: 35133984 Free PMC article. Review.
146 results