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Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation.
Adrover JM, Aroca-Crevillén A, Crainiciuc G, Ostos F, Rojas-Vega Y, Rubio-Ponce A, Cilloniz C, Bonzón-Kulichenko E, Calvo E, Rico D, Moro MA, Weber C, Lizasoaín I, Torres A, Ruiz-Cabello J, Vázquez J, Hidalgo A. Adrover JM, et al. Nat Immunol. 2020 Feb;21(2):135-144. doi: 10.1038/s41590-019-0571-2. Epub 2020 Jan 13. Nat Immunol. 2020. PMID: 31932813 Free PMC article.
Neutrophils scan for activated platelets to initiate inflammation.
Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi MD, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A. Sreeramkumar V, et al. Science. 2014 Dec 5;346(6214):1234-8. doi: 10.1126/science.1256478. Epub 2014 Dec 4. Science. 2014. PMID: 25477463 Free PMC article.
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gómez-del Arco P, Redondo JM, Ruiz-Cabello JM, Jimenez-Borreguero LJ, Enriquez JA, de la Pompa JL, Hidalgo A, Gonzalez S. Gonzalez-Valdes I, et al. Nat Commun. 2015 Mar 9;6:6473. doi: 10.1038/ncomms7473. Nat Commun. 2015. Retraction in: Nat Commun. 2017 Mar 07;8:14006. doi: 10.1038/ncomms14006 PMID: 25751743 Free PMC article. Retracted.
Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.
Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Latorre-Pellicer A, et al. Nature. 2016 Jul 28;535(7613):561-5. doi: 10.1038/nature18618. Epub 2016 Jul 6. Nature. 2016. PMID: 27383793
Corrigendum: Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.
Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Latorre-Pellicer A, et al. Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature20773. Epub 2016 Dec 7. Nature. 2017. PMID: 27926738 No abstract available.
p38γ is essential for cell cycle progression and liver tumorigenesis.
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Tomás-Loba A, et al. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. Nature. 2019. PMID: 30971822
Human influenza A virus causes myocardial and cardiac-specific conduction system infections associated with early inflammation and premature death.
Filgueiras-Rama D, Vasilijevic J, Jalife J, Noujaim SF, Alfonso JM, Nicolas-Avila JA, Gutierrez C, Zamarreño N, Hidalgo A, Bernabé A, Cop CP, Ponce-Balbuena D, Guerrero-Serna G, Calle D, Desco M, Ruiz-Cabello J, Nieto A, Falcon A. Filgueiras-Rama D, et al. Cardiovasc Res. 2021 Feb 22;117(3):876-889. doi: 10.1093/cvr/cvaa117. Cardiovasc Res. 2021. PMID: 32346730 Free PMC article.
182 results