Chen L - Search Results

1

Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.

Chen L, Marsiglia WM, Chen H, Katigbak J, Erdjument-Bromage H, Kemble DJ, Fu L, Ma J, Sun G, Zhang Y, Liang G, Neubert TA, Li X, Traaseth NJ, Mohammadi M. Chen L, et al. Among authors: chen h. Nat Chem Biol. 2020 Mar;16(3):267-277. doi: 10.1038/s41589-019-0455-7. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959966 Free PMC article.

2

Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats.

Hu J, Zhang Y, Dong L, Wang Z, Chen L, Liang D, Shi D, Shan X, Liang G. Hu J, et al. Among authors: chen l. Chem Biol Drug Des. 2015 Jun;85(6):672-84. doi: 10.1111/cbdd.12454. Epub 2014 Nov 6. Chem Biol Drug Des. 2015. PMID: 25327896

3

Synthesis and Anti-Inflammatory Evaluation of Novel C66 Analogs for the Treatment of LPS-Induced Acute Lung Injury.

Feng J, Xiao B, Chen W, Ding T, Chen L, Yu P, Xu F, Zhang H, Liu Z, Liang G. Feng J, et al. Among authors: chen l, chen w. Chem Biol Drug Des. 2015 Oct;86(4):753-63. doi: 10.1111/cbdd.12548. Epub 2015 Mar 20. Chem Biol Drug Des. 2015. PMID: 25727339

4

Curcumin analogue, A13, exhibits anti-leukemia effect via inhibiting STAT3.

Weng Q, Ren L, Guo L, Hu Y, Zhou H, Bao Y, Chen L, Liang G, Wang Y, Ruan J. Weng Q, et al. Among authors: chen l. Tumour Biol. 2016 Jul;37(7):9959-66. doi: 10.1007/s13277-016-4861-0. Epub 2016 Jan 27. Tumour Biol. 2016. PMID: 26815506

5

Determination of the binding mode for anti-inflammatory natural product xanthohumol with myeloid differentiation protein 2.

Fu W, Chen L, Wang Z, Zhao C, Chen G, Liu X, Dai Y, Cai Y, Li C, Zhou J, Liang G. Fu W, et al. Among authors: chen l, chen g. Drug Des Devel Ther. 2016 Jan 27;10:455-63. doi: 10.2147/DDDT.S98466. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 26869767 Free PMC article.

6

EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice.

Li W, Fang Q, Zhong P, Chen L, Wang L, Zhang Y, Wang J, Li X, Wang Y, Wang J, Liang G. Li W, et al. Among authors: chen l. Sci Rep. 2016 Apr 18;6:24580. doi: 10.1038/srep24580. Sci Rep. 2016. PMID: 27087279 Free PMC article.

7

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats.

Zhu H, Xu T, Qiu C, Wu B, Zhang Y, Chen L, Xia Q, Li C, Zhou B, Liu Z, Liang G. Zhu H, et al. Among authors: chen l. Eur J Med Chem. 2016 Oct 4;121:181-193. doi: 10.1016/j.ejmech.2016.05.041. Epub 2016 May 21. Eur J Med Chem. 2016. PMID: 27240273

8

Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells.

Lin R, Zhang Z, Chen L, Zhou Y, Zou P, Feng C, Wang L, Liang G. Lin R, et al. Among authors: chen l. Cancer Lett. 2016 Oct 10;381(1):165-75. doi: 10.1016/j.canlet.2016.07.033. Epub 2016 Jul 28. Cancer Lett. 2016. PMID: 27477901

9

Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations.

Fu W, Chen L, Wang Z, Kang Y, Wu C, Xia Q, Liu Z, Zhou J, Liang G, Cai Y. Fu W, et al. Among authors: chen l. Phys Chem Chem Phys. 2017 Feb 1;19(5):3649-3659. doi: 10.1039/c6cp07964d. Phys Chem Chem Phys. 2017. PMID: 28094372

10

Design, Synthesis, and Structure-Activity Relationship Analysis of Thiazolo[3,2-a]pyrimidine Derivatives with Anti-inflammatory Activity in Acute Lung Injury.

Chen L, Jin Y, Fu W, Xiao S, Feng C, Fang B, Gu Y, Li C, Zhao Y, Liu Z, Liang G. Chen L, et al. ChemMedChem. 2017 Jul 6;12(13):1022-1032. doi: 10.1002/cmdc.201700175. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28503918

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