Levy G - Search Results

1

MPL mutations in essential thrombocythemia uncover a common path of activation with eltrombopag dependent on W491.

Levy G, Carillo S, Papoular B, Cassinat B, Zini JM, Leroy E, Varghese LN, Chachoua I, Defour JP, Smith SO, Constantinescu SN. Levy G, et al. Blood. 2020 Mar 19;135(12):948-953. doi: 10.1182/blood.2019003240. Blood. 2020. PMID: 31978223 Free article.

2

The S505A thrombopoietin receptor mutation in childhood hereditary thrombocytosis and essential thrombocythemia is S505N: single letter amino acid code matters.

Defour JP, Levy G, Leroy E, Smith SO, Constantinescu SN. Defour JP, et al. Among authors: levy g. Leukemia. 2019 Feb;33(2):563-564. doi: 10.1038/s41375-018-0356-x. Epub 2019 Jan 11. Leukemia. 2019. PMID: 30635630 No abstract available.

3

CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag.

Basso-Valentina F, Levy G, Varghese LN, Oufadem M, Neven B, Boussard C, Balayn N, Marty C, Vainchenker W, Plo I, Ballerini P, Constantinescu SN, Favier R, Raslova H. Basso-Valentina F, et al. Among authors: levy g. Blood. 2021 Aug 12;138(6):480-485. doi: 10.1182/blood.2020010567. Blood. 2021. PMID: 34010413 Free article. Clinical Trial.

4

Functional Consequences of Mutations in Myeloproliferative Neoplasms.

Constantinescu SN, Vainchenker W, Levy G, Papadopoulos N. Constantinescu SN, et al. Among authors: levy g. Hemasphere. 2021 Jun 1;5(6):e578. doi: 10.1097/HS9.0000000000000578. eCollection 2021 Jun. Hemasphere. 2021. PMID: 34095761 Free PMC article. Review.

5

MPL S505C enhances driver mutations at W515 in essential thrombocythemia.

Varghese LN, Carreño-Tarragona G, Levy G, Gutiérrez-López de Ocáriz X, Rapado I, Martínez-López J, Ayala R, Constantinescu SN. Varghese LN, et al. Among authors: levy g. Blood Cancer J. 2021 Nov 29;11(11):188. doi: 10.1038/s41408-021-00583-4. Blood Cancer J. 2021. PMID: 34845187 Free PMC article. No abstract available.

6

Targets in MPNs and potential therapeutics.

Levy G, Mambet C, Pecquet C, Bailly S, Havelange V, Diaconu CC, Constantinescu SN. Levy G, et al. Int Rev Cell Mol Biol. 2022;366:41-81. doi: 10.1016/bs.ircmb.2021.06.004. Epub 2021 Sep 23. Int Rev Cell Mol Biol. 2022. PMID: 35153006

7

JAK inhibitors and COVID-19.

Levy G, Guglielmelli P, Langmuir P, Constantinescu SN. Levy G, et al. J Immunother Cancer. 2022 Apr;10(4):e002838. doi: 10.1136/jitc-2021-002838. J Immunother Cancer. 2022. PMID: 35459733 Free PMC article. Review.

8

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers.

Defour JP, Leroy E, Dass S, Balligand T, Levy G, Brett IC, Papadopoulos N, Mouton C, Genet L, Pecquet C, Staerk J, Smith SO, Constantinescu SN. Defour JP, et al. Among authors: levy g. Elife. 2023 Jun 20;12:e81521. doi: 10.7554/eLife.81521. Elife. 2023. PMID: 37338955 Free PMC article.

9

Modulation of human thrombopoietin receptor conformations uncouples JAK2 V617F-driven activation from cytokine-induced stimulation.

Papadopoulos N, Pristavec A, Nédélec A, Levy G, Staerk J, Constantinescu SN. Papadopoulos N, et al. Among authors: levy g. Blood. 2023 Nov 23;142(21):1818-1830. doi: 10.1182/blood.2022019580. Blood. 2023. PMID: 37616564 Free article.

10

Primary cutaneous Ewing sarcoma in a young girl.

Dekeuleneer V, El Nemnom P, Vervier J, Brichard B, Libert J, Van Eeckhout P, Marot L, Tennstedt D, Levy G, De Ville De Goyet M, Boulanger C. Dekeuleneer V, et al. Among authors: levy g. Eur J Dermatol. 2019 Feb 11. doi: 10.1684/ejd.2018.3477. Online ahead of print. Eur J Dermatol. 2019. PMID: 30761992 No abstract available.

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