O'Leary JJ - Search Results

1

Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses.

To EE, O'Leary JJ, O'Neill LAJ, Vlahos R, Bozinovski S, Porter CJH, Brooks RD, Brooks DA, Selemidis S. To EE, et al. Antioxid Redox Signal. 2020 May 1;32(13):982-992. doi: 10.1089/ars.2020.8027. Epub 2020 Mar 6. Antioxid Redox Signal. 2020. PMID: 32008365 Free PMC article. Review.

2

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21.

Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA. Sheedy FJ, et al. Nat Immunol. 2010 Feb;11(2):141-7. doi: 10.1038/ni.1828. Epub 2009 Nov 29. Nat Immunol. 2010. PMID: 19946272

3

TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia.

Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, Fitzgerald KA, Daly S, O'Leary JJ, O'Neill LA. Scharfe-Nugent A, et al. J Immunol. 2012 Jun 1;188(11):5706-12. doi: 10.4049/jimmunol.1103454. Epub 2012 Apr 27. J Immunol. 2012. PMID: 22544937 Free article.

4

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ. d'Adhemar CJ, et al. PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. PLoS One. 2014. PMID: 24977712 Free PMC article.

5

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA. Johnson IR, et al. Oncotarget. 2015 Nov 10;6(35):37919-29. doi: 10.18632/oncotarget.6114. Oncotarget. 2015. PMID: 26473288 Free PMC article.

6

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S. To EE, et al. Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x. Nat Commun. 2017. PMID: 28701733 Free PMC article.

7

MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells.

Sulaiman G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blackshields G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee MY, Campbell EL, Moynagh PN, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ, Gallagher MF. Sulaiman G, et al. Cell Death Differ. 2017 Nov;24(11):1975-1986. doi: 10.1038/cdd.2017.124. Epub 2017 Sep 8. Cell Death Differ. 2017. PMID: 28885616 Free PMC article.

8

NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development.

Harrison IP, Vinh A, Johnson IRD, Luong R, Drummond GR, Sobey CG, Tiganis T, Williams ED, O' Leary JJ, Brooks DA, Selemidis S. Harrison IP, et al. Oncotarget. 2018 Oct 23;9(83):35378-35393. doi: 10.18632/oncotarget.26237. eCollection 2018 Oct 23. Oncotarget. 2018. PMID: 30459931 Free PMC article.

9

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice.

To EE, Erlich J, Liong F, Luong R, Liong S, Bozinovski S, Seow HJ, O'Leary JJ, Brooks DA, Vlahos R, Selemidis S. To EE, et al. Sci Rep. 2019 Feb 20;9(1):2366. doi: 10.1038/s41598-019-38864-5. Sci Rep. 2019. PMID: 30787331 Free PMC article.

10

Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus-induced lung inflammation in mice.

To EE, Luong R, Diao J, O' Leary JJ, Brooks DA, Vlahos R, Selemidis S. To EE, et al. Respirology. 2019 Oct;24(10):1011-1017. doi: 10.1111/resp.13524. Epub 2019 Mar 18. Respirology. 2019. PMID: 30884042 Free PMC article.

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