Zhang L - Search Results

1

Diarylheptanoid: A privileged structure in drug discovery.

Sun DJ, Zhu LJ, Zhao YQ, Zhen YQ, Zhang L, Lin CC, Chen LX. Sun DJ, et al. Among authors: zhang l. Fitoterapia. 2020 Apr;142:104490. doi: 10.1016/j.fitote.2020.104490. Epub 2020 Feb 1. Fitoterapia. 2020. PMID: 32017968 Review.

2

DAW22, a natural sesquiterpene coumarin isolated from Ferula ferulaeoides (Steud.) Korov. that induces C6 glioma cell apoptosis and endoplasmic reticulum (ER) stress.

Zhang L, Tong X, Zhang J, Huang J, Wang J. Zhang L, et al. Among authors: zhang j. Fitoterapia. 2015 Jun;103:46-54. doi: 10.1016/j.fitote.2015.03.010. Epub 2015 Mar 14. Fitoterapia. 2015. PMID: 25776007

3

Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.

Zhang L, Fu L, Zhang S, Zhang J, Zhao Y, Zheng Y, He G, Yang S, Ouyang L, Liu B. Zhang L, et al. Among authors: zhang s, zhang j. Chem Sci. 2017 Apr 1;8(4):2687-2701. doi: 10.1039/c6sc05368h. Epub 2017 Jan 9. Chem Sci. 2017. PMID: 28553505 Free PMC article.

4

Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.

Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B. Ouyang L, et al. Among authors: zhang l, zhang s. J Med Chem. 2017 Dec 28;60(24):9990-10012. doi: 10.1021/acs.jmedchem.7b00275. Epub 2017 Dec 7. J Med Chem. 2017. PMID: 29172540

5

Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment.

Ouyang L, Zhang L, Zhang S, Yao D, Zhao Y, Wang G, Fu L, Lei P, Liu B. Ouyang L, et al. Among authors: zhang l, zhang s. J Med Chem. 2018 Apr 12;61(7):2776-2792. doi: 10.1021/acs.jmedchem.7b01575. Epub 2018 Mar 29. J Med Chem. 2018. PMID: 29561612

6

Design, synthesis and biological evaluation of benzamide derivatives as novel NTCP inhibitors that induce apoptosis in HepG2 cells.

Zhao S, Zhen Y, Fu L, Gao F, Zhou X, Huang S, Zhang L. Zhao S, et al. Among authors: zhang l. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126623. doi: 10.1016/j.bmcl.2019.126623. Epub 2019 Aug 14. Bioorg Med Chem Lett. 2019. PMID: 31439379

7

Dual-target kinase drug design: Current strategies and future directions in cancer therapy.

Sun D, Zhao Y, Zhang S, Zhang L, Liu B, Ouyang L. Sun D, et al. Among authors: zhang l, zhang s. Eur J Med Chem. 2020 Feb 15;188:112025. doi: 10.1016/j.ejmech.2019.112025. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31931340 Review.

8

Discovery of a Novel Dual-Target Inhibitor of ERK1 and ERK5 That Induces Regulated Cell Death to Overcome Compensatory Mechanism in Specific Tumor Types.

Wang G, Zhao Y, Liu Y, Sun D, Zhen Y, Liu J, Fu L, Zhang L, Ouyang L. Wang G, et al. Among authors: zhang l. J Med Chem. 2020 Apr 23;63(8):3976-3995. doi: 10.1021/acs.jmedchem.9b01896. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32078308

9

Targeting autophagy-related protein kinases for potential therapeutic purpose.

Xiang H, Zhang J, Lin C, Zhang L, Liu B, Ouyang L. Xiang H, et al. Among authors: zhang l, zhang j. Acta Pharm Sin B. 2020 Apr;10(4):569-581. doi: 10.1016/j.apsb.2019.10.003. Epub 2019 Oct 18. Acta Pharm Sin B. 2020. PMID: 32322463 Free PMC article. Review.

10

Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.

Zhen Y, Zhao R, Wang M, Jiang X, Gao F, Fu L, Zhang L, Zhou XL. Zhen Y, et al. Among authors: zhang l. Theranostics. 2020 Jul 2;10(18):8080-8097. doi: 10.7150/thno.43473. eCollection 2020. Theranostics. 2020. PMID: 32724459 Free PMC article.

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