Di Stefano G - Search Results

1

Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib.

Bagnolini G, Milano D, Manerba M, Schipani F, Ortega JA, Gioia D, Falchi F, Balboni A, Farabegoli F, De Franco F, Robertson J, Pellicciari R, Pallavicini I, Peri S, Minucci S, Girotto S, Di Stefano G, Roberti M, Cavalli A. Bagnolini G, et al. Among authors: di stefano g. J Med Chem. 2020 Mar 12;63(5):2588-2619. doi: 10.1021/acs.jmedchem.9b01526. Epub 2020 Feb 24. J Med Chem. 2020. PMID: 32037829 Free PMC article.

2

The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow.

Fiume L, Baglioni M, Busi C, Manerba M, Di Stefano G. Fiume L, et al. Among authors: di stefano g. Eur J Pharm Biopharm. 2009 Aug;72(3):630-1. doi: 10.1016/j.ejpb.2009.02.004. Eur J Pharm Biopharm. 2009. PMID: 19572414

3

Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.

Fiume L, Manerba M, Vettraino M, Di Stefano G. Fiume L, et al. Among authors: di stefano g. Pharmacology. 2010;86(3):157-62. doi: 10.1159/000317519. Epub 2010 Aug 10. Pharmacology. 2010. PMID: 20699632

4

Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors.

Fiume L, Vettraino M, Manerba M, Di Stefano G. Fiume L, et al. Among authors: di stefano g. Pharmacol Res. 2011 Apr;63(4):328-34. doi: 10.1016/j.phrs.2010.12.005. Epub 2010 Dec 17. Pharmacol Res. 2011. PMID: 21168502

5

Altered glycosylation profile of purified plasma ACT from Alzheimer's disease.

Ianni M, Manerba M, Di Stefano G, Porcellini E, Chiappelli M, Carbone I, Licastro F. Ianni M, et al. Among authors: di stefano g. Immun Ageing. 2010 Dec 16;7 Suppl 1(Suppl 1):S6. doi: 10.1186/1742-4933-7-S1-S6. Immun Ageing. 2010. PMID: 21172065 Free PMC article.

6

Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells.

Fiume L, Manerba M, Vettraino M, Di Stefano G. Fiume L, et al. Among authors: di stefano g. Eur J Pharmacol. 2011 Nov 16;670(1):39-43. doi: 10.1016/j.ejphar.2011.08.038. Epub 2011 Sep 10. Eur J Pharmacol. 2011. PMID: 21924262

7

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

Manerba M, Vettraino M, Fiume L, Di Stefano G, Sartini A, Giacomini E, Buonfiglio R, Roberti M, Recanatini M. Manerba M, et al. Among authors: di stefano g. ChemMedChem. 2012 Feb 6;7(2):311-7. doi: 10.1002/cmdc.201100471. Epub 2011 Nov 4. ChemMedChem. 2012. PMID: 22052811

8

Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways.

Farabegoli F, Vettraino M, Manerba M, Fiume L, Roberti M, Di Stefano G. Farabegoli F, et al. Among authors: di stefano g. Eur J Pharm Sci. 2012 Nov 20;47(4):729-38. doi: 10.1016/j.ejps.2012.08.012. Epub 2012 Aug 30. Eur J Pharm Sci. 2012. PMID: 22954722

9

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

Vettraino M, Manerba M, Govoni M, Di Stefano G. Vettraino M, et al. Among authors: di stefano g. Anticancer Drugs. 2013 Sep;24(8):862-70. doi: 10.1097/CAD.0b013e328363ae50. Anticancer Drugs. 2013. PMID: 23797802

10

NAD metabolism and functions: a common therapeutic target for neoplastic, metabolic and neurodegenerative diseases.

Di Stefano G, Manerba M, Vettraino M. Di Stefano G, et al. Curr Top Med Chem. 2013;13(23):2918-29. doi: 10.2174/15680266113136660207. Curr Top Med Chem. 2013. PMID: 24171774 Review.

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