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Structural mechanisms of inflammasome assembly.
Lu A, Wu H. Lu A, et al. Among authors: wu h. FEBS J. 2015 Feb;282(3):435-44. doi: 10.1111/febs.13133. Epub 2014 Nov 21. FEBS J. 2015. PMID: 25354325 Free PMC article. Review.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Among authors: wu h. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Wang L, et al. Among authors: wu h. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. Science. 2018. PMID: 30467180 Free PMC article.
Molecular mechanism for NLRP6 inflammasome assembly and activation.
Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H. Shen C, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2052-2057. doi: 10.1073/pnas.1817221116. Epub 2019 Jan 23. Proc Natl Acad Sci U S A. 2019. PMID: 30674671 Free PMC article.
Mechanism of TRPM2 channel gating revealed by cryo-EM.
Xia S, Wang L, Fu TM, Wu H. Xia S, et al. Among authors: wu h. FEBS J. 2019 Sep;286(17):3333-3339. doi: 10.1111/febs.14939. Epub 2019 Jun 10. FEBS J. 2019. PMID: 31144442 Free PMC article. Review.
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