Bechthold E - Search Results

1

Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds.

Temme L, Bechthold E, Schreiber JA, Gawaskar S, Schepmann D, Robaa D, Sippl W, Seebohm G, Wünsch B. Temme L, et al. Among authors: bechthold e. Eur J Med Chem. 2020 Mar 15;190:112138. doi: 10.1016/j.ejmech.2020.112138. Epub 2020 Feb 10. Eur J Med Chem. 2020. PMID: 32070917

2

Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity.

Bechthold E, Schreiber JA, Lehmkuhl K, Frehland B, Schepmann D, Bernal FA, Daniliuc C, Álvarez I, Garcia CV, Schmidt TJ, Seebohm G, Wünsch B. Bechthold E, et al. J Med Chem. 2021 Jan 28;64(2):1170-1179. doi: 10.1021/acs.jmedchem.0c01912. Epub 2021 Jan 10. J Med Chem. 2021. PMID: 33426889

3

Synthesis of tropane-based σ₁ receptor antagonists with antiallodynic activity.

Bechthold E, Schreiber JA, Ritter N, Grey L, Schepmann D, Daniliuc C, González-Cano R, Nieto FR, Seebohm G, Wünsch B. Bechthold E, et al. Eur J Med Chem. 2022 Feb 15;230:114113. doi: 10.1016/j.ejmech.2022.114113. Epub 2022 Jan 13. Eur J Med Chem. 2022. PMID: 35065412

4

Synthesis and biological evaluation of conformationally restricted GluN2B ligands derived from eliprodil.

Bechthold E, Schreiber JA, Ritter N, Schepmann D, Daniliuc C, Seebohm G, Wünsch B. Bechthold E, et al. Eur J Med Chem. 2022 Jul 5;237:114359. doi: 10.1016/j.ejmech.2022.114359. Epub 2022 Apr 14. Eur J Med Chem. 2022. PMID: 35468513

5

Chemical, pharmacodynamic and pharmacokinetic characterization of the GluN2B receptor antagonist 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-1,7-diol - starting point for PET tracer development.

Korff M, Steigerwald R, Bechthold E, Schepmann D, Schreiber JA, Meuth SG, Seebohm G, Wünsch B. Korff M, et al. Among authors: bechthold e. Biol Chem. 2022 Oct 10;404(4):279-289. doi: 10.1515/hsz-2022-0222. Print 2023 Mar 28. Biol Chem. 2022. PMID: 36215695

6

In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs.

Bechthold E, Grey L, Diamant E, Schmidt J, Steigerwald R, Zhao F, Hansen KB, Bunch L, Clausen RP, Wünsch B. Bechthold E, et al. Biol Chem. 2022 Nov 25;404(4):255-265. doi: 10.1515/hsz-2022-0229. Print 2023 Mar 28. Biol Chem. 2022. PMID: 36427206 Free PMC article.

7

Pre-assembled ECMO: Enhancing efficiency and reducing stress in refractory cardiac arrest care.

Thevathasan T, Lech S, Diefenbach A, Bechthold E, Gaßmann T, Fester S, Girke G, Knie W, Lukusa BT, Kühn S, Desch S, Landmesser U, Skurk C. Thevathasan T, et al. Among authors: bechthold e. Resusc Plus. 2024 Oct 18;20:100800. doi: 10.1016/j.resplu.2024.100800. eCollection 2024 Dec. Resusc Plus. 2024. PMID: 39469140 Free PMC article.

8

Value of endometrial biopsies and serum hormone determinations in women with infertility.

Gerhard I, Bechthold E, Eggert-Kruse W, Heberling D, Runnebaum B. Gerhard I, et al. Among authors: bechthold e. Hum Reprod. 1990 Nov;5(8):906-14. doi: 10.1093/oxfordjournals.humrep.a137218. Hum Reprod. 1990. PMID: 2150521

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