Darabedian N - Search Results

1

Translation of Microbiota Short-Chain Fatty Acid Mechanisms Affords Anti-infective Acyl-Salicylic Acid Derivatives.

Yang X, Forster ER, Darabedian N, Kim AT, Pratt MR, Shen A, Hang HC. Yang X, et al. Among authors: darabedian n. ACS Chem Biol. 2020 May 15;15(5):1141-1147. doi: 10.1021/acschembio.9b01009. Epub 2020 Mar 2. ACS Chem Biol. 2020. PMID: 32091869

2

The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular Protein Modification by O-Glucose.

Darabedian N, Gao J, Chuh KN, Woo CM, Pratt MR. Darabedian N, et al. J Am Chem Soc. 2018 Jun 13;140(23):7092-7100. doi: 10.1021/jacs.7b13488. Epub 2018 May 30. J Am Chem Soc. 2018. PMID: 29771506 Free PMC article.

3

Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis.

Darabedian N, Chen TC, Molina H, Pratt MR, Schönthal AH. Darabedian N, et al. ACS Chem Biol. 2018 Nov 16;13(11):3054-3058. doi: 10.1021/acschembio.8b00743. Epub 2018 Nov 7. ACS Chem Biol. 2018. PMID: 30395437

4

Identifying potentially O-GlcNAcylated proteins using metabolic labeling, bioorthogonal enrichment, and Western blotting.

Darabedian N, Pratt MR. Darabedian N, et al. Methods Enzymol. 2019;622:293-307. doi: 10.1016/bs.mie.2019.02.017. Epub 2019 Mar 6. Methods Enzymol. 2019. PMID: 31155058 Free PMC article.

5

MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction.

Pedowitz NJ, Batt AR, Darabedian N, Pratt MR. Pedowitz NJ, et al. Among authors: darabedian n. Nat Chem Biol. 2021 Feb;17(2):169-177. doi: 10.1038/s41589-020-0640-8. Epub 2020 Sep 14. Nat Chem Biol. 2021. PMID: 32929277 Free PMC article.

6

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.

Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. Chuh KN, et al. Among authors: darabedian n. J Am Chem Soc. 2017 Jun 14;139(23):7872-7885. doi: 10.1021/jacs.7b02213. Epub 2017 May 31. J Am Chem Soc. 2017. PMID: 28528544 Free PMC article.

7

Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway.

Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Walter LA, et al. Among authors: darabedian n. Chembiochem. 2018 Sep 17;19(18):1918-1921. doi: 10.1002/cbic.201800280. Epub 2018 Aug 10. Chembiochem. 2018. PMID: 29979493 Free PMC article.

8

Optimization of Chemoenzymatic Mass Tagging by Strain-Promoted Cycloaddition (SPAAC) for the Determination of O-GlcNAc Stoichiometry by Western Blotting.

Darabedian N, Thompson JW, Chuh KN, Hsieh-Wilson LC, Pratt MR. Darabedian N, et al. Biochemistry. 2018 Oct 9;57(40):5769-5774. doi: 10.1021/acs.biochem.8b00648. Epub 2018 Sep 24. Biochemistry. 2018. PMID: 30169966 Free PMC article.

9

O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins.

Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR. Darabedian N, et al. Front Chem. 2020 Apr 28;8:318. doi: 10.3389/fchem.2020.00318. eCollection 2020. Front Chem. 2020. PMID: 32411667 Free PMC article.

10

Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins.

Yarravarapu N, Konada RSR, Darabedian N, Pedowitz NJ, Krishnamurthy SN, Pratt MR, Kohler JJ. Yarravarapu N, et al. Among authors: darabedian n. Bioconjug Chem. 2022 May 18;33(5):781-787. doi: 10.1021/acs.bioconjchem.2c00037. Epub 2022 Apr 19. Bioconjug Chem. 2022. PMID: 35437982 Free PMC article.

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