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HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N. Sivakumaran V, et al. Among authors: toscano jp. Antioxid Redox Signal. 2013 Oct 10;19(11):1185-97. doi: 10.1089/ars.2012.5057. Antioxid Redox Signal. 2013. PMID: 23919584 Free PMC article.
The chemical biology of protein hydropersulfides: Studies of a possible protective function of biological hydropersulfide generation.
Millikin R, Bianco CL, White C, Saund SS, Henriquez S, Sosa V, Akaike T, Kumagai Y, Soeda S, Toscano JP, Lin J, Fukuto JM. Millikin R, et al. Among authors: toscano jp. Free Radic Biol Med. 2016 Aug;97:136-147. doi: 10.1016/j.freeradbiomed.2016.05.013. Epub 2016 May 27. Free Radic Biol Med. 2016. PMID: 27242269 Free PMC article.
Selenols are resistant to irreversible modification by HNO.
Bianco CL, Moore CD, Fukuto JM, Toscano JP. Bianco CL, et al. Among authors: toscano jp. Free Radic Biol Med. 2016 Oct;99:71-78. doi: 10.1016/j.freeradbiomed.2016.07.008. Epub 2016 Jul 14. Free Radic Biol Med. 2016. PMID: 27424037
The chemical biology of HNO signaling.
Bianco CL, Toscano JP, Bartberger MD, Fukuto JM. Bianco CL, et al. Among authors: toscano jp. Arch Biochem Biophys. 2017 Mar 1;617:129-136. doi: 10.1016/j.abb.2016.08.014. Epub 2016 Aug 20. Arch Biochem Biophys. 2017. PMID: 27555493 Free PMC article. Review.
Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?
Bogdándi V, Ida T, Sutton TR, Bianco C, Ditrói T, Koster G, Henthorn HA, Minnion M, Toscano JP, van der Vliet A, Pluth MD, Feelisch M, Fukuto JM, Akaike T, Nagy P. Bogdándi V, et al. Among authors: toscano jp. Br J Pharmacol. 2019 Feb;176(4):646-670. doi: 10.1111/bph.14394. Epub 2018 Aug 23. Br J Pharmacol. 2019. PMID: 29909607 Free PMC article.
77 results