Hoft DF - Search Results

1

Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy.

Liu X, Hoft DF, Peng G. Liu X, et al. Among authors: hoft df. J Clin Invest. 2020 Mar 2;130(3):1073-1083. doi: 10.1172/JCI133679. J Clin Invest. 2020. PMID: 32118585 Free PMC article. Review.

2

Tumor-derived γδ regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence.

Ye J, Ma C, Hsueh EC, Eickhoff CS, Zhang Y, Varvares MA, Hoft DF, Peng G. Ye J, et al. Among authors: hoft df. J Immunol. 2013 Mar 1;190(5):2403-14. doi: 10.4049/jimmunol.1202369. Epub 2013 Jan 25. J Immunol. 2013. PMID: 23355732 Free PMC article.

3

Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition.

Liu X, Mo W, Ye J, Li L, Zhang Y, Hsueh EC, Hoft DF, Peng G. Liu X, et al. Among authors: hoft df. Nat Commun. 2018 Jan 16;9(1):249. doi: 10.1038/s41467-017-02689-5. Nat Commun. 2018. PMID: 29339767 Free PMC article.

4

TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy.

Li L, Liu X, Sanders KL, Edwards JL, Ye J, Si F, Gao A, Huang L, Hsueh EC, Ford DA, Hoft DF, Peng G. Li L, et al. Among authors: hoft df. Cell Metab. 2019 Jan 8;29(1):103-123.e5. doi: 10.1016/j.cmet.2018.09.020. Epub 2018 Oct 18. Cell Metab. 2019. PMID: 30344014 Free PMC article.

5

Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy.

Liu X, Hartman CL, Li L, Albert CJ, Si F, Gao A, Huang L, Zhao Y, Lin W, Hsueh EC, Shen L, Shao Q, Hoft DF, Ford DA, Peng G. Liu X, et al. Among authors: hoft df. Sci Transl Med. 2021 Mar 31;13(587):eaaz6314. doi: 10.1126/scitranslmed.aaz6314. Sci Transl Med. 2021. PMID: 33790024

6

NK and NKT cells have distinct properties and functions in cancer.

Liu X, Li L, Si F, Huang L, Zhao Y, Zhang C, Hoft DF, Peng G. Liu X, et al. Among authors: hoft df. Oncogene. 2021 Jul;40(27):4521-4537. doi: 10.1038/s41388-021-01880-9. Epub 2021 Jun 12. Oncogene. 2021. PMID: 34120141

7

Citrate Promotes Excessive Lipid Biosynthesis and Senescence in Tumor Cells for Tumor Therapy.

Zhao Y, Liu X, Si F, Huang L, Gao A, Lin W, Hoft DF, Shao Q, Peng G. Zhao Y, et al. Among authors: hoft df. Adv Sci (Weinh). 2022 Jan;9(1):e2101553. doi: 10.1002/advs.202101553. Epub 2021 Nov 7. Adv Sci (Weinh). 2022. PMID: 34747157 Free PMC article.

8

Tumor microenvironment metabolites directing T cell differentiation and function.

Liu X, Hoft DF, Peng G. Liu X, et al. Among authors: hoft df. Trends Immunol. 2022 Feb;43(2):132-147. doi: 10.1016/j.it.2021.12.004. Epub 2021 Dec 29. Trends Immunol. 2022. PMID: 34973923 Free PMC article. Review.

9

TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence.

Ye J, Ma C, Hsueh EC, Dou J, Mo W, Liu S, Han B, Huang Y, Zhang Y, Varvares MA, Hoft DF, Peng G. Ye J, et al. Among authors: hoft df. EMBO Mol Med. 2014 Oct;6(10):1294-311. doi: 10.15252/emmm.201403918. EMBO Mol Med. 2014. PMID: 25231413 Free PMC article.

10

Tumor microenvironments direct the recruitment and expansion of human Th17 cells.

Su X, Ye J, Hsueh EC, Zhang Y, Hoft DF, Peng G. Su X, et al. Among authors: hoft df. J Immunol. 2010 Feb 1;184(3):1630-41. doi: 10.4049/jimmunol.0902813. Epub 2009 Dec 21. J Immunol. 2010. PMID: 20026736

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