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A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity.
Gall L, Jardi F, Lammens L, Piñero J, Souza TM, Rodrigues D, Jennen DGJ, de Kok TM, Coyle L, Chung SW, Ferreira S, Jo H, Beattie KA, Kelly C, Duckworth CA, Pritchard DM, Pin C. Gall L, et al. Among authors: pin c. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1511-1528. doi: 10.1002/psp4.13029. Epub 2023 Sep 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37621010 Free PMC article.
Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants.
Jardi F, Kelly C, Teague C, Fowler-Williams H, Sevin DC, Rodrigues D, Jo H, Ferreira S, Herpers B, Van Heerden M, de Kok T, Pin C, Lynch A, Duckworth CA, De Jonghe S, Lammens L, Pritchard DM. Jardi F, et al. Among authors: pin c. Arch Toxicol. 2023 Jan;97(1):235-254. doi: 10.1007/s00204-022-03374-3. Epub 2022 Oct 6. Arch Toxicol. 2023. PMID: 36203040
176 results