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Structurally Minimalized and Druglike TGase2 Inhibitors Based on 7-Aminoquinoline-5,8-dione Scaffolds for the Treatment of Diabetic Retinopathy.
Kang J, Jeon HY, Lee J, Bae S, Park GY, Min KJ, Joo J, Lee AJ, Kim HJ, Im CY, Kim EB, Lee JH, Hwang JS, Lee S, Lee JY, Navals P, Keillor JW, Ha KS, Song M. Kang J, et al. Among authors: keillor jw. J Med Chem. 2024 Nov 14;67(21):19716-19735. doi: 10.1021/acs.jmedchem.4c02081. Epub 2024 Oct 24. J Med Chem. 2024. PMID: 39445793
Acyl transfer mechanisms of tissue transglutaminase.
Keillor JW, Clouthier CM, Apperley KYP, Akbar A, Mulani A. Keillor JW, et al. Bioorg Chem. 2014 Dec;57:186-197. doi: 10.1016/j.bioorg.2014.06.003. Epub 2014 Jun 25. Bioorg Chem. 2014. PMID: 25035302 Review.
Inhibition or ablation of transglutaminase 2 impairs astrocyte migration.
Monteagudo A, Ji C, Akbar A, Keillor JW, Johnson GVW. Monteagudo A, et al. Among authors: keillor jw. Biochem Biophys Res Commun. 2017 Jan 22;482(4):942-947. doi: 10.1016/j.bbrc.2016.11.137. Epub 2016 Nov 27. Biochem Biophys Res Commun. 2017. PMID: 27899316 Free PMC article.
112 results