Chen Y - Search Results

1

A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Among authors: chen y. Sci Rep. 2020 Mar 6;10(1):4203. doi: 10.1038/s41598-020-61082-3. Sci Rep. 2020. PMID: 32144367 Free PMC article.

2

A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.

Khaled HG, Feng H, Hu X, Sun X, Zheng W, Li PP, Rudnicki DD, Ye W, Chen YC, Southall N, Marugan J, Ross CA, Ferrer M, Henderson MJ, Margolis RL. Khaled HG, et al. Sci Rep. 2021 Mar 17;11(1):6157. doi: 10.1038/s41598-021-85279-2. Sci Rep. 2021. PMID: 33731741 Free PMC article.

3

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

Dorjsuren D, Eastman RT, Song MJ, Yasgar A, Chen Y, Bharti K, Zakharov AV, Jadhav A, Ferrer M, Shi PY, Simeonov A. Dorjsuren D, et al. Among authors: chen y. PLoS One. 2022 Jan 18;17(1):e0261821. doi: 10.1371/journal.pone.0261821. eCollection 2022. PLoS One. 2022. PMID: 35041689 Free PMC article.

4

Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Among authors: chen y. Sci Rep. 2022 Oct 13;12(1):17185. doi: 10.1038/s41598-022-21947-1. Sci Rep. 2022. PMID: 36229506 Free PMC article. No abstract available.

5

Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.

Song MJ, Quinn R, Nguyen E, Hampton C, Sharma R, Park TS, Koster C, Voss T, Tristan C, Weber C, Singh A, Dejene R, Bose D, Chen YC, Derr P, Derr K, Michael S, Barone F, Chen G, Boehm M, Maminishkis A, Singec I, Ferrer M, Bharti K. Song MJ, et al. Nat Methods. 2023 Jan;20(1):149-161. doi: 10.1038/s41592-022-01701-1. Epub 2022 Dec 22. Nat Methods. 2023. PMID: 36550275

6

A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.

Boutin ME, Strong CE, Van Hese B, Hu X, Itkin Z, Chen YC, LaCroix A, Gordon R, Guicherit O, Carromeu C, Kundu S, Lee E, Ferrer M. Boutin ME, et al. SLAS Discov. 2022 Jun;27(4):209-218. doi: 10.1016/j.slasd.2022.01.003. Epub 2022 Jan 31. SLAS Discov. 2022. PMID: 35092840 Free PMC article.

7

Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform.

Jung O, Tung YT, Sim E, Chen YC, Lee E, Ferrer M, Song MJ. Jung O, et al. Biofabrication. 2022 Feb 14;14(2):10.1088/1758-5090/ac32a5. doi: 10.1088/1758-5090/ac32a5. Biofabrication. 2022. PMID: 35166694 Free PMC article.

8

Genome-scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells.

Xiao S, Chen YC, Buehler E, Mandal S, Mandal A, Betenbaugh M, Park MH, Martin S, Shiloach J. Xiao S, et al. Biotechnol Bioeng. 2016 Nov;113(11):2403-15. doi: 10.1002/bit.26017. Epub 2016 Sep 21. Biotechnol Bioeng. 2016. PMID: 27215166 Free PMC article.

9

Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening.

Auld DS, Jimenez M, Yue K, Busby S, Chen YC, Bowes S, Wendel G, Smith T, Zhang JH. Auld DS, et al. J Biomol Screen. 2016 Dec;21(10):1075-1089. doi: 10.1177/1087057116667255. Epub 2016 Sep 27. J Biomol Screen. 2016. PMID: 27601436

10

A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein.

McCormack NM, Abera MB, Arnold ES, Gibbs RM, Martin SE, Buehler E, Chen YC, Chen L, Fischbeck KH, Burnett BG. McCormack NM, et al. Cell Rep. 2021 May 11;35(6):109125. doi: 10.1016/j.celrep.2021.109125. Cell Rep. 2021. PMID: 33979606 Free PMC article.

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