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Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.
Wolff AM, Young ID, Sierra RG, Brewster AS, Martynowycz MW, Nango E, Sugahara M, Nakane T, Ito K, Aquila A, Bhowmick A, Biel JT, Carbajo S, Cohen AE, Cortez S, Gonzalez A, Hino T, Im D, Koralek JD, Kubo M, Lazarou TS, Nomura T, Owada S, Samelson AJ, Tanaka T, Tanaka R, Thompson EM, van den Bedem H, Woldeyes RA, Yumoto F, Zhao W, Tono K, Boutet S, Iwata S, Gonen T, Sauter NK, Fraser JS, Thompson MC. Wolff AM, et al. Among authors: im d. IUCrJ. 2020 Feb 26;7(Pt 2):306-323. doi: 10.1107/S205225252000072X. eCollection 2020 Mar 1. IUCrJ. 2020. PMID: 32148858 Free PMC article.
A three-dimensional movie of structural changes in bacteriorhodopsin.
Nango E, Royant A, Kubo M, Nakane T, Wickstrand C, Kimura T, Tanaka T, Tono K, Song C, Tanaka R, Arima T, Yamashita A, Kobayashi J, Hosaka T, Mizohata E, Nogly P, Sugahara M, Nam D, Nomura T, Shimamura T, Im D, Fujiwara T, Yamanaka Y, Jeon B, Nishizawa T, Oda K, Fukuda M, Andersson R, Båth P, Dods R, Davidsson J, Matsuoka S, Kawatake S, Murata M, Nureki O, Owada S, Kameshima T, Hatsui T, Joti Y, Schertler G, Yabashi M, Bondar AN, Standfuss J, Neutze R, Iwata S. Nango E, et al. Among authors: im d. Science. 2016 Dec 23;354(6319):1552-1557. doi: 10.1126/science.aah3497. Science. 2016. PMID: 28008064
Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Suno R, Kimura KT, Nakane T, Yamashita K, Wang J, Fujiwara T, Yamanaka Y, Im D, Horita S, Tsujimoto H, Tawaramoto MS, Hirokawa T, Nango E, Tono K, Kameshima T, Hatsui T, Joti Y, Yabashi M, Shimamoto K, Yamamoto M, Rosenbaum DM, Iwata S, Shimamura T, Kobayashi T. Suno R, et al. Among authors: im d. Structure. 2018 Jan 2;26(1):7-19.e5. doi: 10.1016/j.str.2017.11.005. Epub 2017 Dec 7. Structure. 2018. PMID: 29225076 Free article.
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone.
Im D, Inoue A, Fujiwara T, Nakane T, Yamanaka Y, Uemura T, Mori C, Shiimura Y, Kimura KT, Asada H, Nomura N, Tanaka T, Yamashita A, Nango E, Tono K, Kadji FMN, Aoki J, Iwata S, Shimamura T. Im D, et al. Nat Commun. 2020 Dec 22;11(1):6442. doi: 10.1038/s41467-020-20221-0. Nat Commun. 2020. PMID: 33353947 Free PMC article.
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography.
Wolff AM, Nango E, Young ID, Brewster AS, Kubo M, Nomura T, Sugahara M, Owada S, Barad BA, Ito K, Bhowmick A, Carbajo S, Hino T, Holton JM, Im D, O'Riordan LJ, Tanaka T, Tanaka R, Sierra RG, Yumoto F, Tono K, Iwata S, Sauter NK, Fraser JS, Thompson MC. Wolff AM, et al. Among authors: im d. Nat Chem. 2023 Nov;15(11):1549-1558. doi: 10.1038/s41557-023-01329-4. Epub 2023 Sep 18. Nat Chem. 2023. PMID: 37723259 Free PMC article.
S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation.
Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M. Toyomoto M, et al. Among authors: im d. Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9. doi: 10.1016/j.chembiol.2021.01.004. Epub 2021 Feb 8. Cell Chem Biol. 2021. PMID: 33561428 Free article.
642 results