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Blockade of interleukin-2-inducible T-cell kinase signaling attenuates acute lung injury in mice through adjustment of pulmonary Th17/Treg immune responses and reduction of oxidative stress.
Nadeem A, Al-Harbi NO, Ahmad SF, Al-Harbi MM, Alhamed AS, Alfardan AS, Assiri MA, Ibrahim KE, Albassam H. Nadeem A, et al. Among authors: ibrahim ke. Int Immunopharmacol. 2020 Jun;83:106369. doi: 10.1016/j.intimp.2020.106369. Epub 2020 Mar 9. Int Immunopharmacol. 2020. PMID: 32163900
Inhibition of spleen tyrosine kinase attenuates psoriasis-like inflammation in mice through blockade of dendritic cell-Th17 inflammation axis.
Alzahrani KS, Nadeem A, Ahmad SF, Al-Harbi NO, Ibrahim KE, El-Sherbeeny AM, Alhoshani AR, Alshammari MA, Alotaibi MR, Al-Harbi MM. Alzahrani KS, et al. Among authors: ibrahim ke. Biomed Pharmacother. 2019 Mar;111:347-358. doi: 10.1016/j.biopha.2018.12.060. Epub 2018 Dec 25. Biomed Pharmacother. 2019. PMID: 30593001 Free article.
Inhibition of spleen tyrosine kinase signaling protects against acute lung injury through blockade of NADPH oxidase and IL-17A in neutrophils and γδ T cells respectively in mice.
Nadeem A, Ahmad SF, Al-Harbi NO, Al-Harbi MM, Ibrahim KE, Kundu S, Attia SM, Alanazi WA, AlSharari SD. Nadeem A, et al. Among authors: ibrahim ke. Int Immunopharmacol. 2019 Mar;68:39-47. doi: 10.1016/j.intimp.2018.12.062. Epub 2019 Jan 2. Int Immunopharmacol. 2019. PMID: 30611000
Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice.
Nadeem A, Ahmad SF, Al-Harbi NO, Attia SM, Bakheet SA, Ibrahim KE, Alqahtani F, Alqinyah M. Nadeem A, et al. Among authors: ibrahim ke. Behav Brain Res. 2019 May 17;364:213-224. doi: 10.1016/j.bbr.2019.02.031. Epub 2019 Feb 19. Behav Brain Res. 2019. PMID: 30790585
Protease activated receptor-2 mediated upregulation of IL-17 receptor signaling on airway epithelial cells is responsible for neutrophilic infiltration during acute exposure of house dust mite allergens in mice.
Nadeem A, Al-Harbi NO, Ahmad SF, Ibrahim KE, Alotaibi MR, Siddiqui N, Alsharari SD, Attia SM, Al-Harbi MM. Nadeem A, et al. Among authors: ibrahim ke. Chem Biol Interact. 2019 May 1;304:52-60. doi: 10.1016/j.cbi.2019.03.001. Epub 2019 Mar 7. Chem Biol Interact. 2019. PMID: 30853428
Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways.
Al-Harbi NO, Nadeem A, Ahmad SF, AlThagfan SS, Alqinyah M, Alqahtani F, Ibrahim KE, Al-Harbi MM. Al-Harbi NO, et al. Among authors: ibrahim ke. Eur J Pharmacol. 2019 Jul 15;855:276-284. doi: 10.1016/j.ejphar.2019.05.026. Epub 2019 May 14. Eur J Pharmacol. 2019. PMID: 31100413
118 results