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Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Zhang Z, et al. Among authors: sengupta s. Nature. 2020 Mar;579(7799):415-420. doi: 10.1038/s41586-020-2071-9. Epub 2020 Mar 11. Nature. 2020. PMID: 32188940 Free PMC article.
BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells.
Debruyne DN, Dries R, Sengupta S, Seruggia D, Gao Y, Sharma B, Huang H, Moreau L, McLane M, Day DS, Marco E, Chen T, Gray NS, Wong KK, Orkin SH, Yuan GC, Young RA, George RE. Debruyne DN, et al. Among authors: sengupta s. Nature. 2019 Aug;572(7771):676-680. doi: 10.1038/s41586-019-1472-0. Epub 2019 Aug 7. Nature. 2019. PMID: 31391581 Free PMC article.
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.
Sengupta S, Das S, Crespo AC, Cornel AM, Patel AG, Mahadevan NR, Campisi M, Ali AK, Sharma B, Rowe JH, Huang H, Debruyne DN, Cerda ED, Krajewska M, Dries R, Chen M, Zhang S, Soriano L, Cohen MA, Versteeg R, Jaenisch R, Spranger S, Romee R, Miller BC, Barbie DA, Nierkens S, Dyer MA, Lieberman J, George RE. Sengupta S, et al. Nat Cancer. 2022 Oct;3(10):1228-1246. doi: 10.1038/s43018-022-00427-5. Epub 2022 Sep 22. Nat Cancer. 2022. PMID: 36138189 Free PMC article.
Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration.
Huang H, Gont A, Kee L, Dries R, Pfeifer K, Sharma B, Debruyne DN, Harlow M, Sengupta S, Guan J, Yeung CM, Wang W, Hallberg B, Palmer RH, Irwin MS, George RE. Huang H, et al. Among authors: sengupta s. Cell Rep. 2021 Jul 13;36(2):109363. doi: 10.1016/j.celrep.2021.109363. Cell Rep. 2021. PMID: 34260934 Free PMC article.
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Cornel AM, Dunnebach E, Hofman DA, Das S, Sengupta S, van den Ham F, Wienke J, Strijker JGM, van den Beemt DAMH, Essing AHW, Koopmans B, Engels SAG, Lo Presti V, Szanto CS, George RE, Molenaar JJ, van Heesch S, Dierselhuis MP, Nierkens S. Cornel AM, et al. Among authors: sengupta s. J Immunother Cancer. 2022 Dec;10(12):e005002. doi: 10.1136/jitc-2022-005002. J Immunother Cancer. 2022. PMID: 36521927 Free PMC article.
Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras.
Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Cohen MA, et al. Among authors: sengupta s. Cell Stem Cell. 2020 Apr 2;26(4):579-592.e6. doi: 10.1016/j.stem.2020.02.001. Epub 2020 Mar 5. Cell Stem Cell. 2020. PMID: 32142683 Free PMC article.
CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Qin X, Lam A, Zhang X, Sengupta S, Iorgulescu JB, Ni H, Das S, Rager M, Zhou Z, Zuo T, Meara GK, Floru AE, Kemet C, Veerapaneni D, Kashy D, Lin L, Lloyd K, Kwok L, Smith KS, Nagaraju RT, Meijers R, Ceol C, Liu CT, Alexandrescu S, Wu CJ, Keskin DB, George RE, Feng H. Qin X, et al. Among authors: sengupta s. Sci Adv. 2024 Mar 15;10(11):eadh9547. doi: 10.1126/sciadv.adh9547. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489372 Free PMC article.
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
Gorman BR, Voloudakis G, Igo RP Jr, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W; VA Million Veteran Program; International AMD Genomics Consortium (IAMDGC); Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Gorman BR, et al. Nat Genet. 2024 Dec 2. doi: 10.1038/s41588-024-01764-0. Online ahead of print. Nat Genet. 2024. PMID: 39623103
2,986 results