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Page 1
TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer.
Zhao B, Dierichs L, Gu JN, Trajkovic-Arsic M, Axel Hilger R, Savvatakis K, Vega-Rubin-de-Celis S, Liffers ST, Peña-Llopis S, Behrens D, Hahn S, Siveke JT, Lueong SS. Zhao B, et al. Among authors: savvatakis k. Cell Death Discov. 2020 Mar 11;6:12. doi: 10.1038/s41420-020-0246-7. eCollection 2020. Cell Death Discov. 2020. PMID: 32194992 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33563931
Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Cheung PF, Neff F, Neander C, Bazarna A, Savvatakis K, Liffers ST, Althoff K, Lee CL, Moding EJ, Kirsch DG, Saur D, Bazhin AV, Trajkovic-Arsic M, Heikenwalder MF, Siveke JT. Cheung PF, et al. Among authors: savvatakis k. Cancer Res. 2018 Sep 1;78(17):4997-5010. doi: 10.1158/0008-5472.CAN-18-0052. Epub 2018 May 29. Cancer Res. 2018. PMID: 29844119
A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery.
Schug C, Gupta A, Urnauer S, Steiger K, Cheung PF, Neander C, Savvatakis K, Schmohl KA, Trajkovic-Arsic M, Schwenk N, Schwaiger M, Nelson PJ, Siveke JT, Spitzweg C. Schug C, et al. Among authors: savvatakis k. Mol Cancer Res. 2019 Jan;17(1):310-320. doi: 10.1158/1541-7786.MCR-18-0185. Epub 2018 Sep 17. Mol Cancer Res. 2019. PMID: 30224540
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT. Cheung PF, et al. Among authors: savvatakis k. Nat Commun. 2022 Jan 10;13(1):156. doi: 10.1038/s41467-021-27088-9. Nat Commun. 2022. PMID: 35013174 Free PMC article.
Antitumor immune response is associated with favorable survival in GEP-NEN G3.
Rosery V, Reis H, Savvatakis K, Kowall B, Stuschke M, Paul A, Dechêne A, Yang J, Zhao B, Borgers A, Kasper S, Schuler M, Cheung PF, Siveke JT. Rosery V, et al. Among authors: savvatakis k. Endocr Relat Cancer. 2021 Sep 2;28(10):683-693. doi: 10.1530/ERC-21-0223. Endocr Relat Cancer. 2021. PMID: 34472429
Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta.
Karageorgiadi DM, Tsilimigras DI, Selemenakis P, Vlachou V, de Lastic AL, Rodi M, Chatziathanasiou D, Savvatakis K, Antoniou N, Deli AC, Papalampros A, Filis KA, Mouzaki A, Varvarigou A, Zografos G, Gorgoulis VG, Pateras IS, Sigala F. Karageorgiadi DM, et al. Among authors: savvatakis k. Sci Rep. 2020 Mar 19;10(1):5040. doi: 10.1038/s41598-020-61268-9. Sci Rep. 2020. PMID: 32193441 Free PMC article.
Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma.
Heid I, Münch C, Karakaya S, Lueong SS, Winkelkotte AM, Liffers ST, Godfrey L, Cheung PFY, Savvatakis K, Topping GJ, Englert F, Kritzner L, Grashei M, Tannapfel A, Viebahn R, Wolters H, Uhl W, Vangala D, Smeets EMM, Aarntzen EHJG, Rauh D, Weichert W, Hoheisel JD, Hahn SA, Schilling F, Braren R, Trajkovic-Arsic M, Siveke JT. Heid I, et al. Among authors: savvatakis k. Cancer Metab. 2022 Dec 9;10(1):24. doi: 10.1186/s40170-022-00298-5. Cancer Metab. 2022. PMID: 36494842 Free PMC article.