Ebrahim HY - Search Results

1

Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons.

Halawa AH, Elgammal WE, Hassan SM, Hassan AH, Nassar HS, Ebrahim HY, Mehany ABM, El-Agrody AM. Halawa AH, et al. Among authors: ebrahim hy. Bioorg Chem. 2020 May;98:103725. doi: 10.1016/j.bioorg.2020.103725. Epub 2020 Mar 6. Bioorg Chem. 2020. PMID: 32199303

2

Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.

Abdelwahed KS, Siddique AB, Ebrahim HY, Qusa MH, Mudhish EA, Rad AH, Zerfaoui M, Abd Elmageed ZY, El Sayed KA. Abdelwahed KS, et al. Among authors: ebrahim hy. Mar Drugs. 2023 Mar 28;21(4):215. doi: 10.3390/md21040215. Mar Drugs. 2023. PMID: 37103355 Free PMC article.

3

Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.

McGehee OC, Ebrahim HY, Rad AH, Abdelwahed KS, Mudhish EA, King JA, Helal IE, Meyer SA, El Sayed KA. McGehee OC, et al. Among authors: ebrahim hy. Molecules. 2023 Feb 2;28(3):1460. doi: 10.3390/molecules28031460. Molecules. 2023. PMID: 36771126 Free PMC article.

4

The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion.

Mady MS, Mohyeldin MM, Ebrahim HY, Elsayed HE, Houssen WE, Haggag EG, Soliman RF, El Sayed KA. Mady MS, et al. Among authors: ebrahim hy. Bioorg Med Chem. 2016 Jan 15;24(2):113-22. doi: 10.1016/j.bmc.2015.11.038. Epub 2015 Nov 28. Bioorg Med Chem. 2016. PMID: 26692349 Free PMC article.

5

(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies.

Ebrahim HY, Mohyeldin MM, Hailat MM, El Sayed KA. Ebrahim HY, et al. Bioorg Med Chem. 2016 Nov 15;24(22):5748-5761. doi: 10.1016/j.bmc.2016.09.032. Epub 2016 Sep 13. Bioorg Med Chem. 2016. PMID: 27681240 Free PMC article.

6

The tobacco cembranoid (1S,2E,4S,7E,11E)-2,7,11-cembratriene-4,6-diol as a novel angiogenesis inhibitory lead for the control of breast malignancies.

Hailat MM, Ebrahim HY, Mohyeldin MM, Goda AA, Siddique AB, El Sayed KA. Hailat MM, et al. Among authors: ebrahim hy. Bioorg Med Chem. 2017 Aug 1;25(15):3911-3921. doi: 10.1016/j.bmc.2017.05.028. Epub 2017 May 20. Bioorg Med Chem. 2017. PMID: 28583806

7

Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies.

Elsayed HE, Ebrahim HY, Haggag EG, Kamal AM, El Sayed KA. Elsayed HE, et al. Among authors: ebrahim hy. Bioorg Med Chem. 2017 Dec 15;25(24):6297-6312. doi: 10.1016/j.bmc.2017.09.033. Epub 2017 Sep 27. Bioorg Med Chem. 2017. PMID: 29066046

8

Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors.

Halawa AH, Eskandrani AA, Elgammal WE, Hassan SM, Hassan AH, Ebrahim HY, Mehany ABM, El-Agrody AM, Okasha RM. Halawa AH, et al. Among authors: ebrahim hy. Int J Mol Sci. 2019 Nov 8;20(22):5592. doi: 10.3390/ijms20225592. Int J Mol Sci. 2019. PMID: 31717402 Free PMC article.

9

3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells.

Akl MR, Elsayed HE, Ebrahim HY, Haggag EG, Kamal AM, El Sayed KA. Akl MR, et al. Among authors: ebrahim hy. Eur J Pharmacol. 2014 Oct 5;740:209-17. doi: 10.1016/j.ejphar.2014.07.011. Epub 2014 Jul 18. Eur J Pharmacol. 2014. PMID: 25046839

10

Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies.

Elsayed HE, Ebrahim HY, Mohyeldin MM, Siddique AB, Kamal AM, Haggag EG, El Sayed KA. Elsayed HE, et al. Among authors: ebrahim hy. Nutr Cancer. 2017 Nov-Dec;69(8):1256-1271. doi: 10.1080/01635581.2017.1367936. Epub 2017 Oct 30. Nutr Cancer. 2017. PMID: 29083228 Free PMC article.

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