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Amelioration of elastase-induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice.
Fysikopoulos A, Seimetz M, Hadzic S, Knoepp F, Wu CY, Malkmus K, Wilhelm J, Pichl A, Bednorz M, Tadele Roxlau E, Ghofrani HA, Sommer N, Gierhardt M, Schermuly RT, Seeger W, Grimminger F, Weissmann N, Kraut S. Fysikopoulos A, et al. Among authors: wu cy. Br J Pharmacol. 2021 Jan;178(1):152-171. doi: 10.1111/bph.15057. Epub 2020 Apr 28. Br J Pharmacol. 2021. PMID: 32201936 Free article.
Lung epithelium damage in COPD - An unstoppable pathological event?
Hadzic S, Wu CY, Avdeev S, Weissmann N, Schermuly RT, Kosanovic D. Hadzic S, et al. Among authors: wu cy. Cell Signal. 2020 Apr;68:109540. doi: 10.1016/j.cellsig.2020.109540. Epub 2020 Jan 15. Cell Signal. 2020. PMID: 31953012 Review.
Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung.
Gouveia L, Kraut S, Hadzic S, Vazquéz-Liébanas E, Kojonazarov B, Wu CY, Veith C, He L, Mermelekas G, Schermuly RT, Weissmann N, Betsholtz C, Andrae J. Gouveia L, et al. Among authors: wu cy. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L831-L843. doi: 10.1152/ajplung.00295.2019. Epub 2020 Mar 18. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32186397 Free PMC article.
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadzic S, Gredic M, Parajuli N, Kojonazarov B, Kraut S, Wilhelm J, Knoepp F, Henneke I, Pichl A, Kanbagli ZI, Scheibe S, Fysikopoulos A, Wu CY, Klepetko W, Jaksch P, Eichstaedt C, Grünig E, Hinderhofer K, Geiszt M, Müller N, Rezende F, Buchmann G, Wittig I, Hecker M, Hecker A, Padberg W, Dorfmüller P, Gattenlöhner S, Vogelmeier CF, Günther A, Karnati S, Baumgart-Vogt E, Schermuly RT, Ghofrani HA, Seeger W, Schröder K, Grimminger F, Brandes RP, Weissmann N. Seimetz M, et al. Among authors: wu cy. Nat Metab. 2020 Jun;2(6):532-546. doi: 10.1038/s42255-020-0215-8. Epub 2020 Jun 8. Nat Metab. 2020. PMID: 32694733
Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadzic S, Gredic M, Parajuli N, Kojonazarov B, Kraut S, Wilhelm J, Knoepp F, Henneke I, Pichl A, Kanbagli ZI, Scheibe S, Fysikopoulos A, Wu CY, Klepetko W, Jaksch P, Eichstaedt C, Grünig E, Hinderhofer K, Geiszt M, Müller N, Rezende F, Buchmann G, Wittig I, Hecker M, Hecker A, Padberg W, Dorfmüller P, Gattenlöhner S, Vogelmeier CF, Günther A, Karnati S, Baumgart-Vogt E, Schermuly RT, Ghofrani HA, Seeger W, Schröder K, Grimminger F, Brandes RP, Weissmann N. Seimetz M, et al. Among authors: wu cy. Nat Metab. 2020 Jul;2(7):648. doi: 10.1038/s42255-020-0248-z. Nat Metab. 2020. PMID: 32694792
The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension.
Hadzic S, Wu CY, Gredic M, Kojonazarov B, Pak O, Kraut S, Sommer N, Kosanovic D, Grimminger F, Schermuly RT, Seeger W, Bellusci S, Weissmann N. Hadzic S, et al. Among authors: wu cy. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L903-L915. doi: 10.1152/ajplung.00048.2021. Epub 2021 Mar 24. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33760647 Free article.
Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice.
Gredic M, Wu CY, Hadzic S, Pak O, Savai R, Kojonazarov B, Doswada S, Weiss A, Weigert A, Guenther A, Brandes RP, Schermuly RT, Grimminger F, Seeger W, Sommer N, Kraut S, Weissmann N. Gredic M, et al. Among authors: wu cy. Eur Respir J. 2022 Apr 7;59(4):2101153. doi: 10.1183/13993003.01153-2021. Print 2022 Apr. Eur Respir J. 2022. PMID: 34475225 Free PMC article.
SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension.
Veith C, Vartürk-Özcan I, Wujak M, Hadzic S, Wu CY, Knoepp F, Kraut S, Petrovic A, Gredic M, Pak O, Brosien M, Heimbrodt M, Wilhelm J, Weisel FC, Malkmus K, Schäfer K, Gall H, Tello K, Kosanovic D, Sydykov A, Sarybaev A, Günther A, Brandes RP, Seeger W, Grimminger F, Ghofrani HA, Schermuly RT, Kwapiszewska G, Sommer N, Weissmann N. Veith C, et al. Among authors: wu cy. Circulation. 2022 Mar 22;145(12):916-933. doi: 10.1161/CIRCULATIONAHA.121.057001. Epub 2022 Feb 17. Circulation. 2022. PMID: 35175782
3,437 results