Sawyers CL - Search Results

1

Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG.

Wasmuth EV, Hoover EA, Antar A, Klinge S, Chen Y, Sawyers CL. Wasmuth EV, et al. Among authors: sawyers cl. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8584-8592. doi: 10.1073/pnas.1922159117. Epub 2020 Mar 27. Proc Natl Acad Sci U S A. 2020. PMID: 32220959 Free PMC article.

2

Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis.

Scher HI, Sawyers CL. Scher HI, et al. Among authors: sawyers cl. J Clin Oncol. 2005 Nov 10;23(32):8253-61. doi: 10.1200/JCO.2005.03.4777. J Clin Oncol. 2005. PMID: 16278481 Review.

3

Targeting the androgen receptor pathway in prostate cancer.

Chen Y, Sawyers CL, Scher HI. Chen Y, et al. Among authors: sawyers cl. Curr Opin Pharmacol. 2008 Aug;8(4):440-8. doi: 10.1016/j.coph.2008.07.005. Epub 2008 Aug 12. Curr Opin Pharmacol. 2008. PMID: 18674639 Free PMC article. Review.

4

Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer.

Welsbie DS, Xu J, Chen Y, Borsu L, Scher HI, Rosen N, Sawyers CL. Welsbie DS, et al. Among authors: sawyers cl. Cancer Res. 2009 Feb 1;69(3):958-66. doi: 10.1158/0008-5472.CAN-08-2216. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176386 Free PMC article.

5

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: sawyers cl. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

6

Coordinate transcriptional regulation by ERG and androgen receptor in fusion-positive prostate cancers.

Chen Y, Sawyers CL. Chen Y, et al. Among authors: sawyers cl. Cancer Cell. 2010 May 18;17(5):415-6. doi: 10.1016/j.ccr.2010.04.022. Cancer Cell. 2010. PMID: 20478521 Free PMC article.

7

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor.

Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, Kim K, Sawyers CL. Watson PA, et al. Among authors: sawyers cl. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16759-65. doi: 10.1073/pnas.1012443107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823238 Free PMC article.

8

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.

Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL. Chi P, et al. Among authors: sawyers cl. Nature. 2010 Oct 14;467(7317):849-53. doi: 10.1038/nature09409. Epub 2010 Oct 3. Nature. 2010. PMID: 20927104 Free PMC article.

9

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.

Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL. Carver BS, et al. Among authors: sawyers cl. Cancer Cell. 2011 May 17;19(5):575-86. doi: 10.1016/j.ccr.2011.04.008. Cancer Cell. 2011. PMID: 21575859 Free PMC article.

10

Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen.

Evans MJ, Smith-Jones PM, Wongvipat J, Navarro V, Kim S, Bander NH, Larson SM, Sawyers CL. Evans MJ, et al. Among authors: sawyers cl. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9578-82. doi: 10.1073/pnas.1106383108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606347 Free PMC article.

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