Costa KD - Search Results

1

Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients.

Wong AO, Wong N, Geng L, Chow MZ, Lee EK, Wu H, Khine M, Kong CW, Costa KD, Keung W, Cheung YF, Li RA. Wong AO, et al. Among authors: costa kd. Front Physiol. 2020 Mar 12;11:165. doi: 10.3389/fphys.2020.00165. eCollection 2020. Front Physiol. 2020. PMID: 32226389 Free PMC article.

2

Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias.

Wang J, Chen A, Lieu DK, Karakikes I, Chen G, Keung W, Chan CW, Hajjar RJ, Costa KD, Khine M, Li RA. Wang J, et al. Among authors: costa kd. Biomaterials. 2013 Nov;34(35):8878-86. doi: 10.1016/j.biomaterials.2013.07.039. Epub 2013 Aug 12. Biomaterials. 2013. PMID: 23942210

3

Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs.

Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Chen G, et al. Among authors: costa kd. Circ Arrhythm Electrophysiol. 2015 Feb;8(1):193-202. doi: 10.1161/CIRCEP.114.002049. Epub 2014 Dec 10. Circ Arrhythm Electrophysiol. 2015. PMID: 25504561 Free PMC article.

4

Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification.

Lee EK, Tran DD, Keung W, Chan P, Wong G, Chan CW, Costa KD, Li RA, Khine M. Lee EK, et al. Among authors: costa kd. Stem Cell Reports. 2017 Nov 14;9(5):1560-1572. doi: 10.1016/j.stemcr.2017.09.008. Epub 2017 Oct 12. Stem Cell Reports. 2017. PMID: 29033305 Free PMC article.

5

Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies.

Lieu DK, Turnbull IC, Costa KD, Li RA. Lieu DK, et al. Among authors: costa kd. Drug Discov Today Dis Models. 2012 Winter;9(4):e209-e217. doi: 10.1016/j.ddmod.2012.06.002. Drug Discov Today Dis Models. 2012. PMID: 29422934 Free PMC article.

6

Human Cardiac Ventricular-Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two-Tiered Assay for Inotropic Responses.

Keung W, Chan PKW, Backeris PC, Lee EK, Wong N, Wong AOT, Wong GKY, Chan CWY, Fermini B, Costa KD, Li RA. Keung W, et al. Among authors: costa kd. Clin Pharmacol Ther. 2019 Aug;106(2):402-414. doi: 10.1002/cpt.1385. Epub 2019 Mar 28. Clin Pharmacol Ther. 2019. PMID: 30723889

7

Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues.

Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA. Chow MZ, et al. Among authors: costa kd. Sci Rep. 2019 May 16;9(1):7502. doi: 10.1038/s41598-019-42953-w. Sci Rep. 2019. PMID: 31097748 Free PMC article.

8

Sarco/endoplasmic reticulum Ca²⁺-ATPase is a more effective calcium remover than sodium-calcium exchanger in human embryonic stem cell-derived cardiomyocytes.

Li S, Chopra A, Keung W, Chan CWY, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Li S, et al. Among authors: costa kd. Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H1105-H1115. doi: 10.1152/ajpheart.00540.2018. Epub 2019 Jul 26. Am J Physiol Heart Circ Physiol. 2019. PMID: 31347915 Free article.

9

[No title available]

[No authors listed] [No authors listed] PMID: 31962920

10

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues.

Wong AO, Gurung B, Wong WS, Mak SY, Tse WW, Li CM, Lieu DK, Costa KD, Li RA, Hajjar RJ. Wong AO, et al. Among authors: costa kd. J Mol Cell Cardiol. 2021 Apr;153:106-110. doi: 10.1016/j.yjmcc.2020.12.014. Epub 2020 Dec 27. J Mol Cell Cardiol. 2021. PMID: 33373642 Free PMC article.

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