Roper DI - Search Results

1

The Extracellular Domain of Two-component System Sensor Kinase VanS from Streptomyces coelicolor Binds Vancomycin at a Newly Identified Binding Site.

Lockey C, Edwards RJ, Roper DI, Dixon AM. Lockey C, et al. Among authors: roper di. Sci Rep. 2020 Mar 31;10(1):5727. doi: 10.1038/s41598-020-62557-z. Sci Rep. 2020. PMID: 32235931 Free PMC article.

2

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase.

Usha V, Lloyd AJ, Roper DI, Dowson CG, Kozlov G, Gehring K, Chauhan S, Imam HT, Blindauer CA, Besra GS. Usha V, et al. Among authors: roper di. Sci Rep. 2016 Mar 15;6:23191. doi: 10.1038/srep23191. Sci Rep. 2016. PMID: 26976706 Free PMC article.

3

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein.

Teo ACK, Lee SC, Pollock NL, Stroud Z, Hall S, Thakker A, Pitt AR, Dafforn TR, Spickett CM, Roper DI. Teo ACK, et al. Among authors: roper di. Sci Rep. 2019 Feb 12;9(1):1813. doi: 10.1038/s41598-018-37962-0. Sci Rep. 2019. PMID: 30755655 Free PMC article.

4

Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ.

Lee SC, Collins R, Lin YP, Jamshad M, Broughton C, Harris SA, Hanson BS, Tognoloni C, Parslow RA, Terry AE, Rodger A, Smith CJ, Edler KJ, Ford R, Roper DI, Dafforn TR. Lee SC, et al. Among authors: roper di. Sci Rep. 2019 Dec 10;9(1):18712. doi: 10.1038/s41598-019-54999-x. Sci Rep. 2019. PMID: 31822696 Free PMC article.

5

Substitutions in PBP2b from β-Lactam-resistant Streptococcus pneumoniae Have Different Effects on Enzymatic Activity and Drug Reactivity.

Calvez P, Breukink E, Roper DI, Dib M, Contreras-Martel C, Zapun A. Calvez P, et al. Among authors: roper di. J Biol Chem. 2017 Feb 17;292(7):2854-2865. doi: 10.1074/jbc.M116.764696. Epub 2017 Jan 6. J Biol Chem. 2017. PMID: 28062575 Free PMC article.

6

Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane.

York A, Lloyd AJ, Del Genio CI, Shearer J, Hinxman KJ, Fritz K, Fulop V, Dowson CG, Khalid S, Roper DI. York A, et al. Among authors: roper di. Structure. 2021 Jul 1;29(7):731-742.e6. doi: 10.1016/j.str.2021.03.001. Epub 2021 Mar 18. Structure. 2021. PMID: 33740396 Free PMC article.

7

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.

Micelli C, Dai Y, Raustad N, Isberg RR, Dowson CG, Lloyd AJ, Geisinger E, Crow A, Roper DI. Micelli C, et al. Among authors: roper di. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215237120. doi: 10.1073/pnas.2215237120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787358 Free PMC article.

8

Adenosine phosphonate inhibitors of lipid II: alanyl tRNA ligase MurM from Streptococcus pneumoniae.

Cressina E, Lloyd AJ, De Pascale G, Roper DI, Dowson CG, Bugg TD. Cressina E, et al. Among authors: roper di. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4654-6. doi: 10.1016/j.bmcl.2007.05.071. Epub 2007 May 25. Bioorg Med Chem Lett. 2007. PMID: 17548193

9

Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex.

Ruane KM, Lloyd AJ, Fülöp V, Dowson CG, Barreteau H, Boniface A, Dementin S, Blanot D, Mengin-Lecreulx D, Gobec S, Dessen A, Roper DI. Ruane KM, et al. Among authors: roper di. J Biol Chem. 2013 Nov 15;288(46):33439-48. doi: 10.1074/jbc.M113.508135. Epub 2013 Sep 24. J Biol Chem. 2013. PMID: 24064214 Free PMC article.

10

Identification of a novel inhibition site in translocase MraY based upon the site of interaction with lysis protein E from bacteriophage ϕX174.

Rodolis MT, Mihalyi A, O'Reilly A, Slikas J, Roper DI, Hancock RE, Bugg TD. Rodolis MT, et al. Among authors: roper di. Chembiochem. 2014 Jun 16;15(9):1300-8. doi: 10.1002/cbic.201402064. Epub 2014 Jun 4. Chembiochem. 2014. PMID: 24895118

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