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106 results

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Page 1
Discovery of a selective inhibitor of doublecortin like kinase 1.
Ferguson FM, Nabet B, Raghavan S, Liu Y, Leggett AL, Kuljanin M, Kalekar RL, Yang A, He S, Wang J, Ng RWS, Sulahian R, Li L, Poulin EJ, Huang L, Koren J, Dieguez-Martinez N, Espinosa S, Zeng Z, Corona CR, Vasta JD, Ohi R, Sim T, Kim ND, Harshbarger W, Lizcano JM, Robers MB, Muthaswamy S, Lin CY, Look AT, Haigis KM, Mancias JD, Wolpin BM, Aguirre AJ, Hahn WC, Westover KD, Gray NS. Ferguson FM, et al. Among authors: nabet b. Nat Chem Biol. 2020 Jun;16(6):635-643. doi: 10.1038/s41589-020-0506-0. Epub 2020 Apr 6. Nat Chem Biol. 2020. PMID: 32251410 Free PMC article.
Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function.
Trory JS, Munkacsi A, Śledź KM, Vautrinot J, Goudswaard LJ, Jackson ML, Heesom KJ, Moore SF, Poole AW, Nabet B, Aggarwal VK, Hers I. Trory JS, et al. Among authors: nabet b. Blood Adv. 2023 May 9;7(9):1692-1696. doi: 10.1182/bloodadvances.2022008466. Blood Adv. 2023. PMID: 36342848 Free PMC article.
Transcription control by the ENL YEATS domain in acute leukaemia.
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, Dhe-Paganon S, Zhang F, Orkin SH, Winter GE, Bradner JE. Erb MA, et al. Among authors: nabet b. Nature. 2017 Mar 9;543(7644):270-274. doi: 10.1038/nature21688. Epub 2017 Mar 1. Nature. 2017. PMID: 28241139 Free PMC article.
MELK is not necessary for the proliferation of basal-like breast cancer cells.
Huang HT, Seo HS, Zhang T, Wang Y, Jiang B, Li Q, Buckley DL, Nabet B, Roberts JM, Paulk J, Dastjerdi S, Winter GE, McLauchlan H, Moran J, Bradner JE, Eck MJ, Dhe-Paganon S, Zhao JJ, Gray NS. Huang HT, et al. Among authors: nabet b. Elife. 2017 Sep 19;6:e26693. doi: 10.7554/eLife.26693. Elife. 2017. PMID: 28926338 Free PMC article.
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma.
Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, Westbrook TF, Chesler L, Lin CY, Bradner JE. Zeid R, et al. Among authors: nabet b. Nat Genet. 2018 Apr;50(4):515-523. doi: 10.1038/s41588-018-0044-9. Epub 2018 Jan 29. Nat Genet. 2018. PMID: 29379199 Free PMC article.
The dTAG system for immediate and target-specific protein degradation.
Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE. Nabet B, et al. Nat Chem Biol. 2018 May;14(5):431-441. doi: 10.1038/s41589-018-0021-8. Epub 2018 Mar 26. Nat Chem Biol. 2018. PMID: 29581585 Free PMC article.
It Takes Two To Target: A Study in KRAS Dimerization.
Nabet B, Gray NS. Nabet B, et al. Biochemistry. 2018 Apr 24;57(16):2289-2290. doi: 10.1021/acs.biochem.8b00376. Epub 2018 Apr 12. Biochemistry. 2018. PMID: 29648795 No abstract available.
106 results