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Page 1
Discovery of a selective inhibitor of doublecortin like kinase 1.
Ferguson FM, Nabet B, Raghavan S, Liu Y, Leggett AL, Kuljanin M, Kalekar RL, Yang A, He S, Wang J, Ng RWS, Sulahian R, Li L, Poulin EJ, Huang L, Koren J, Dieguez-Martinez N, Espinosa S, Zeng Z, Corona CR, Vasta JD, Ohi R, Sim T, Kim ND, Harshbarger W, Lizcano JM, Robers MB, Muthaswamy S, Lin CY, Look AT, Haigis KM, Mancias JD, Wolpin BM, Aguirre AJ, Hahn WC, Westover KD, Gray NS. Ferguson FM, et al. Among authors: ohi r. Nat Chem Biol. 2020 Jun;16(6):635-643. doi: 10.1038/s41589-020-0506-0. Epub 2020 Apr 6. Nat Chem Biol. 2020. PMID: 32251410 Free PMC article.
Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes.
Dumas ME, Chen GY, Kendrick ND, Xu G, Larsen SD, Jana S, Waterson AG, Bauer JA, Hancock W, Sulikowski GA, Ohi R. Dumas ME, et al. Among authors: ohi r. Bioorg Med Chem Lett. 2019 Jan 15;29(2):148-154. doi: 10.1016/j.bmcl.2018.12.008. Epub 2018 Dec 4. Bioorg Med Chem Lett. 2019. PMID: 30528696 Free PMC article.
Kinesin-5 inhibitor resistance is driven by kinesin-12.
Sturgill EG, Norris SR, Guo Y, Ohi R. Sturgill EG, et al. Among authors: ohi r. J Cell Biol. 2016 Apr 25;213(2):213-27. doi: 10.1083/jcb.201507036. Epub 2016 Apr 18. J Cell Biol. 2016. PMID: 27091450 Free PMC article.
Microtubule minus-end stability is dictated by the tubulin off-rate.
Strothman C, Farmer V, Arpağ G, Rodgers N, Podolski M, Norris S, Ohi R, Zanic M. Strothman C, et al. Among authors: ohi r. J Cell Biol. 2019 Sep 2;218(9):2841-2853. doi: 10.1083/jcb.201905019. Epub 2019 Aug 16. J Cell Biol. 2019. PMID: 31420452 Free PMC article.
199 results