Su Y - Search Results

1

Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia.

Luedtke DA, Su Y, Ma J, Li X, Buck SA, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Lin H, Taub JW, Ge Y. Luedtke DA, et al. Among authors: su y. Signal Transduct Target Ther. 2020 Feb 26;5(1):17. doi: 10.1038/s41392-020-0112-3. Signal Transduct Target Ther. 2020. PMID: 32296028 Free PMC article.

2

Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells.

Ma J, Li X, Su Y, Zhao J, Luedtke DA, Epshteyn V, Edwards H, Wang G, Wang Z, Chu R, Taub JW, Lin H, Wang Y, Ge Y. Ma J, et al. Among authors: su y. Sci Rep. 2017 Feb 8;7:41950. doi: 10.1038/srep41950. Sci Rep. 2017. PMID: 28176818 Free PMC article.

3

Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo.

Su Y, Li X, Ma J, Zhao J, Liu S, Wang G, Edwards H, Taub JW, Lin H, Ge Y. Su Y, et al. Biochem Pharmacol. 2018 Feb;148:13-26. doi: 10.1016/j.bcp.2017.11.022. Epub 2017 Dec 5. Biochem Pharmacol. 2018. PMID: 29208365 Free PMC article.

4

Inhibition of XPO1 enhances cell death induced by ABT-199 in acute myeloid leukaemia via Mcl-1.

Luedtke DA, Su Y, Liu S, Edwards H, Wang Y, Lin H, Taub JW, Ge Y. Luedtke DA, et al. Among authors: su y. J Cell Mol Med. 2018 Dec;22(12):6099-6111. doi: 10.1111/jcmm.13886. Epub 2018 Sep 14. J Cell Mol Med. 2018. PMID: 30596398 Free PMC article.

5

Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia.

Li X, Su Y, Madlambayan G, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Ma J, Knight T, Wang G, Wang Y, Yang J, Taub JW, Lin H, Ge Y. Li X, et al. Among authors: su y. Haematologica. 2019 Nov;104(11):2225-2240. doi: 10.3324/haematol.2018.201343. Epub 2019 Feb 28. Haematologica. 2019. PMID: 30819918 Free PMC article.

6

Venetoclax Synergistically Enhances the Anti-leukemic Activity of Vosaroxin Against Acute Myeloid Leukemia Cells Ex Vivo.

Liu F, Knight T, Su Y, Edwards H, Wang G, Wang Y, Taub JW, Lin H, Sun L, Ge Y. Liu F, et al. Among authors: su y. Target Oncol. 2019 Jun;14(3):351-364. doi: 10.1007/s11523-019-00638-4. Target Oncol. 2019. PMID: 31115744

7

The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.

Li X, Su Y, Hege K, Madlambayan G, Edwards H, Knight T, Polin L, Kushner J, Dzinic SH, White K, Yang J, Miller R, Wang G, Zhao L, Wang Y, Lin H, Taub JW, Ge Y. Li X, et al. Among authors: su y. Haematologica. 2021 May 1;106(5):1262-1277. doi: 10.3324/haematol.2019.233445. Haematologica. 2021. PMID: 32165486 Free PMC article.

8

Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.

Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y. Liu F, et al. Among authors: su y. Cancers (Basel). 2020 Aug 24;12(9):2400. doi: 10.3390/cancers12092400. Cancers (Basel). 2020. PMID: 32847115 Free PMC article.

9

Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy.

Carter JL, Hege K, Yang J, Kalpage HA, Su Y, Edwards H, Hüttemann M, Taub JW, Ge Y. Carter JL, et al. Among authors: su y. Signal Transduct Target Ther. 2020 Dec 18;5(1):288. doi: 10.1038/s41392-020-00361-x. Signal Transduct Target Ther. 2020. PMID: 33335095 Free PMC article. Review.

10

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.

Qiao X, Ma J, Knight T, Su Y, Edwards H, Polin L, Li J, Kushner J, Dzinic SH, White K, Wang J, Lin H, Wang Y, Wang L, Wang G, Taub JW, Ge Y. Qiao X, et al. Among authors: su y. Blood Cancer J. 2021 Jun 7;11(6):111. doi: 10.1038/s41408-021-00502-7. Blood Cancer J. 2021. PMID: 34099621 Free PMC article.

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