Ibrahim TS - Search Results

1

Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold.

Ibrahim TS, Salem IM, Mostafa SM, El-Sabbagh OI, ElKhamisi MKM, Hegazy L, Elgendy B. Ibrahim TS, et al. Bioorg Chem. 2020 Jul;100:103878. doi: 10.1016/j.bioorg.2020.103878. Epub 2020 Apr 26. Bioorg Chem. 2020. PMID: 32361486

2

Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors.

Taher ES, Ibrahim TS, Fares M, Al-Mahmoudy AMM, Radwan AF, Orabi KY, El-Sabbagh OI. Taher ES, et al. Among authors: ibrahim ts. Eur J Med Chem. 2019 Jun 1;171:372-382. doi: 10.1016/j.ejmech.2019.03.042. Epub 2019 Mar 20. Eur J Med Chem. 2019. PMID: 30928709

3

Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors.

Ibrahim TS, Bokhtia RM, Al-Mahmoudy AMM, Taher ES, AlAwadh MA, Elagawany M, Abdel-Aal EH, Panda S, Gouda AM, Asfour HZ, Alhakamy NA, Youssif BGM. Ibrahim TS, et al. Bioorg Chem. 2020 Jun;99:103782. doi: 10.1016/j.bioorg.2020.103782. Epub 2020 Mar 24. Bioorg Chem. 2020. PMID: 32229348

4

Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity.

Ibrahim TS, Sheha TA, Abo-Dya NE, AlAwadh MA, Alhakamy NA, Abdel-Samii ZK, Panda SS, Abuo-Rahma GEA, Mohamed MFA. Ibrahim TS, et al. Bioorg Chem. 2020 Jun;99:103797. doi: 10.1016/j.bioorg.2020.103797. Epub 2020 Mar 30. Bioorg Chem. 2020. PMID: 32247939

5

The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme.

Malebari AM, Ibrahim TS, Salem IM, Salama I, Khayyat AN, Mostafa SM, El-Sabbagh OI, Darwish KM. Malebari AM, et al. Among authors: ibrahim ts. Pharmaceuticals (Basel). 2020 Sep 18;13(9):252. doi: 10.3390/ph13090252. Pharmaceuticals (Basel). 2020. PMID: 32961906 Free PMC article.

6

Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.

Ibrahim TS, Hawwas MM, Taher ES, Alhakamy NA, Alfaleh MA, Elagawany M, Elgendy B, Zayed GM, Mohamed MFA, Abdel-Samii ZK, Elshaier YAMM. Ibrahim TS, et al. Bioorg Chem. 2020 Dec;105:104352. doi: 10.1016/j.bioorg.2020.104352. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33080494

7

Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.

Ibrahim TS, Almalki AJ, Moustafa AH, Allam RM, Abuo-Rahma GEA, El Subbagh HI, Mohamed MFA. Ibrahim TS, et al. Bioorg Chem. 2021 Jun;111:104885. doi: 10.1016/j.bioorg.2021.104885. Epub 2021 Apr 1. Bioorg Chem. 2021. PMID: 33838559

8

Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.

Ghanim AM, Rezq S, Ibrahim TS, Romero DG, Kothayer H. Ghanim AM, et al. Among authors: ibrahim ts. Eur J Med Chem. 2021 Jul 5;219:113457. doi: 10.1016/j.ejmech.2021.113457. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33892270 Free PMC article.

9

Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction.

Ibrahim TS, Moustafa AH, Almalki AJ, Allam RM, Althagafi A, Md S, Mohamed MFA. Ibrahim TS, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1067-1078. doi: 10.1080/14756366.2021.1929201. J Enzyme Inhib Med Chem. 2021. PMID: 34027787 Free PMC article.

10

New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2.

Seliem IA, Panda SS, Girgis AS, Moatasim Y, Kandeil A, Mostafa A, Ali MA, Nossier ES, Rasslan F, Srour AM, Sakhuja R, Ibrahim TS, Abdel-Samii ZKM, Al-Mahmoudy AMM. Seliem IA, et al. Among authors: ibrahim ts. Bioorg Chem. 2021 Sep;114:105117. doi: 10.1016/j.bioorg.2021.105117. Epub 2021 Jun 23. Bioorg Chem. 2021. PMID: 34214752 Free PMC article.

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