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Page 1
Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
Huang W, Navarro-Serer B, Jeong YJ, Chianchiano P, Xia L, Luchini C, Veronese N, Dowiak C, Ng T, Trujillo MA, Huang B, Pflüger MJ, Macgregor-Das AM, Lionheart G, Jones D, Fujikura K, Nguyen-Ngoc KV, Neumann NM, Groot VP, Hasanain A, van Oosten AF, Fischer SE, Gallinger S, Singhi AD, Zureikat AH, Brand RE, Gaida MM, Heinrich S, Burkhart RA, He J, Wolfgang CL, Goggins MG, Thompson ED, Roberts NJ, Ewald AJ, Wood LD. Huang W, et al. Among authors: lionheart g. Cancer Res. 2020 Jul 1;80(13):2804-2817. doi: 10.1158/0008-5472.CAN-19-1523. Epub 2020 May 6. Cancer Res. 2020. PMID: 32376602 Free PMC article.
IPMNs with co-occurring invasive cancers: neighbours but not always relatives.
Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD. Felsenstein M, et al. Among authors: lionheart g. Gut. 2018 Sep;67(9):1652-1662. doi: 10.1136/gutjnl-2017-315062. Epub 2018 Mar 2. Gut. 2018. PMID: 29500184 Free PMC article.
Pancreatic undifferentiated carcinoma with osteoclast-like giant cells is genetically similar to, but clinically distinct from, conventional ductal adenocarcinoma.
Luchini C, Pea A, Lionheart G, Mafficini A, Nottegar A, Veronese N, Chianchiano P, Brosens LA, Noë M, Offerhaus GJA, Yonescu R, Ning Y, Malleo G, Riva G, Piccoli P, Cataldo I, Capelli P, Zamboni G, Scarpa A, Wood LD. Luchini C, et al. Among authors: lionheart g. J Pathol. 2017 Oct;243(2):148-154. doi: 10.1002/path.4941. Epub 2017 Sep 5. J Pathol. 2017. PMID: 28722124 Free PMC article.
Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion.
Hong SM, Jung D, Kiemen A, Gaida MM, Yoshizawa T, Braxton AM, Noë M, Lionheart G, Oshima K, Thompson ED, Burkhart R, Wu PH, Wirtz D, Hruban RH, Wood LD. Hong SM, et al. Among authors: lionheart g. Mod Pathol. 2020 Apr;33(4):639-647. doi: 10.1038/s41379-019-0409-3. Epub 2019 Nov 7. Mod Pathol. 2020. PMID: 31700162 Free PMC article.
The Impact of Clinical and Pathological Features on Intraductal Papillary Mucinous Neoplasm Recurrence After Surgical Resection: Long-Term Follow-Up Analysis.
Pflüger MJ, Griffin JF, Hackeng WM, Kawamoto S, Yu J, Chianchiano P, Shin E, Lionheart G, Tsai HL, Wang H, Rezaee N, Burkhart RA, Cameron JL, Thompson ED, Wolfgang CL, He J, Brosens LAA, Wood LD. Pflüger MJ, et al. Among authors: lionheart g. Ann Surg. 2022 Jun 1;275(6):1165-1174. doi: 10.1097/SLA.0000000000004427. Epub 2020 Nov 17. Ann Surg. 2022. PMID: 33214420 Free PMC article.