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The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.
Dahal S, Cheng R, Cheung PK, Been T, Malty R, Geng M, Manianis S, Shkreta L, Jahanshahi S, Toutant J, Chan R, Park S, Brockman MA, Babu M, Mubareka S, Mossman K, Banerjee A, Gray-Owen S, Brown M, Houry WA, Chabot B, Grierson D, Cochrane A. Dahal S, et al. Viruses. 2021 Dec 30;14(1):60. doi: 10.3390/v14010060. Viruses. 2021. PMID: 35062264 Free PMC article.
Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.
Dahal S, Clayton K, Been T, Fernet-Brochu R, Ocando AV, Balachandran A, Poirier M, Maldonado RK, Shkreta L, Boligan KF, Guvenc F, Rahman F, Branch D, Bell B, Chabot B, Gray-Owen SD, Parent LJ, Cochrane A. Dahal S, et al. Retrovirology. 2022 Aug 19;19(1):18. doi: 10.1186/s12977-022-00605-4. Retrovirology. 2022. PMID: 35986377 Free PMC article.
On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine.
Dahal S, Clayton K, Cabral T, Cheng R, Jahanshahi S, Ahmed C, Koirala A, Villasmil Ocando A, Malty R, Been T, Hernandez J, Mangos M, Shen D, Babu M, Calarco J, Chabot B, Attisano L, Houry WA, Cochrane A. Dahal S, et al. J Virol. 2023 Oct 31;97(10):e0039623. doi: 10.1128/jvi.00396-23. Epub 2023 Sep 14. J Virol. 2023. PMID: 37706687 Free PMC article.
Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies.
Mao YQ, Jahanshahi S, Malty R, Van Ommen DAJ, Wan Y, Morey TM, Chuang SHW, Pavlova V, Ahmed C, Dahal S, Lin F, Mangos M, Nurtanto J, Song Y, Been T, Christie-Holmes N, Gray-Owen SD, Babu M, Wong AP, Batey RA, Attisano L, Cochrane A, Houry WA. Mao YQ, et al. Among authors: dahal s. Commun Biol. 2024 Nov 7;7(1):1460. doi: 10.1038/s42003-024-07143-z. Commun Biol. 2024. PMID: 39511285 Free PMC article.
315 results