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A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harnden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. Sparks RP, et al. Among authors: zhang c. J Biol Chem. 2019 Nov 15;294(46):17168-17185. doi: 10.1074/jbc.RA119.008865. Epub 2019 Sep 12. J Biol Chem. 2019. PMID: 31515268 Free PMC article.
High throughput analysis of vacuolar acidification.
Zhang C, Balutowski A, Feng Y, Calderin JD, Fratti RA. Zhang C, et al. Anal Biochem. 2022 Dec 1;658:114927. doi: 10.1016/j.ab.2022.114927. Epub 2022 Sep 24. Anal Biochem. 2022. PMID: 36167157
Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harnden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. Sparks RP, et al. Among authors: zhang c. J Biol Chem. 2022 Nov;298(11):102576. doi: 10.1016/j.jbc.2022.102576. Epub 2022 Oct 15. J Biol Chem. 2022. PMID: 36257250 Free PMC article. No abstract available.
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